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尼日利亚一只陆龟(加拉帕戈斯象龟)患横纹肌肉瘤:病例报告

Rhabdomyosarcoma in a terrestrial tortoise (Geochelone nigra) in Nigeria: a case report.

作者信息

Eyarefe Oghenemega D, Antia Richard E, Oguntoye Cecilia O, Abiola Olusoji O, Alaka Olugbenga O, Ogunsola John O

机构信息

Department of Veterinary Surgery and Reproduction, University of Ibadan, Nigeria.

出版信息

J S Afr Vet Assoc. 2012 Nov 30;83(1):300. doi: 10.4102/jsava.v83i1.300.

DOI:10.4102/jsava.v83i1.300
PMID:23327150
Abstract

A skeletal muscle tumour (rhabdomysarcoma) was diagnosed in a 4-year-old captive female terrestrial tortoise (Geochelone nigra) weighing 7 kg presented at the Veterinary Teaching Hospital, University of Ibadan, Ibadan, Nigeria. The tumour was located at the anterior right portion of the body and ventral to the carapace. The location of the tumour prevented the tortoise from extending its head from the body. The tumour was a sessile, smooth white mass, with a soft myxomatous consistency. The histological features that were diagnostic of rhabdomyosarcoma included a sparse population of haphazardly arranged spindle-shaped cells within a homogenous matrix (anisocytosis), occasional tumour giant and binucleate cells, and some well differentiated myofibrils with cross striations within the cytoplasm. The paucity of information on tumours in the land tortoise was the reason for this report, which appears to be the first report of rhabdomyosarcoma in the tortoise.

摘要

在尼日利亚伊巴丹大学兽医学院教学医院,对一只体重7千克、4岁的圈养雌性陆龟(黑陆龟)进行诊断,发现其患有骨骼肌肿瘤(横纹肌肉瘤)。肿瘤位于身体右前部,背甲下方。肿瘤的位置使陆龟无法将头部从身体伸出。肿瘤为无柄、光滑的白色肿物,质地呈柔软的黏液瘤样。诊断为横纹肌肉瘤的组织学特征包括:在均匀基质内有少量杂乱排列的梭形细胞(细胞大小不一),偶尔可见肿瘤巨细胞和双核细胞,以及细胞质内一些分化良好的有横纹的肌原纤维。撰写本报告的原因是关于陆龟肿瘤的信息匮乏,而本报告似乎是首例关于陆龟横纹肌肉瘤的报道。

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