老年非洲巨鼠（库氏非洲巨鼠）的自发性横纹肌肉瘤

Spontaneous rhabdomyosarcomas in aged Mastomys (Praomys coucha).

作者信息

Madarame H, Kashimoto Y, Kawamoto T, Toyonaga S, Hasegawa Y

机构信息

Department of Laboratory Animal Science, School of Veterinary Medicine and Animal Sciences, Kitasato University, Aomori, Japan.

出版信息

Lab Anim. 1995 Oct;29(4):464-9. doi: 10.1258/002367795780740078.

DOI:10.1258/002367795780740078

PMID:8558834

Abstract

Two spontaneous tumours in the hind leg of 2 aged Mastomys were diagnosed as poorly differentiated rhabdomyosarcomas. In both cases, the neoplastic cells had no evidence of cross-striation, but had a positive reaction for muscle-specific proteins. This is the second report of rhabdomyosarcomas in Mastomys, and the first described in detail.

摘要

在2只老年多乳鼠的后腿中发现了2个自发肿瘤，经诊断为低分化横纹肌肉瘤。在这两个病例中，肿瘤细胞均无横纹的迹象，但对肌肉特异性蛋白呈阳性反应。这是关于多乳鼠横纹肌肉瘤的第二篇报道，也是第一篇详细描述的报道。