Suzuki M, Sitizyo K, Takeuchi T
Department of Veterinary Physiology, Faculty of Agriculture, Tottori University, Japan.
Nihon Seirigaku Zasshi. 1990;52(2):47-53.
The present study was designed to establish visual evoked potential (VEP) as one of clinical tests for veterinary medicine. Experiments were carried out on eight adult male guinea pigs weighed 350 to 750 g. We investigated influences of click sound, luminous intensity and habituation on VEP patterns. The VEP of the guinea pig was composed of primary (P 10, N 20, P 30, N 40) and secondary (P 55, N 75, P 100, N 140) components, followed by a rhythmic after-discharge. Click sound with flash produced some unclear peaks in VEP, while click sound without flash elicited clear six peaks. These different components of the response to stimulation suggested that the acoustically evoked potential induced some peaks in VEP. With the intensity used in the present study, changes in luminous intensity resulted in unrecognizable difference among the VEPs. Early components of VEP were not clearly influenced by the habituation to stimulation. As the stimulation was repeated, rhythmic after-discharge seemed to be suppressed in the half of experiments.
本研究旨在将视觉诱发电位（VEP）确立为兽医学的临床检测方法之一。对8只体重在350至750克之间的成年雄性豚鼠进行了实验。我们研究了点击声、光强度和习惯化对VEP模式的影响。豚鼠的VEP由初级成分（P10、N20、P30、N40）和次级成分（P55、N75、P100、N140）组成，随后是有节奏的后放电。有闪光的点击声在VEP中产生了一些不清晰的峰值，而无闪光的点击声则引出了清晰的六个峰值。对刺激的这些不同反应成分表明，听觉诱发电位在VEP中诱发了一些峰值。在本研究使用的强度下，光强度的变化导致VEP之间的差异无法识别。VEP的早期成分不受刺激习惯化的明显影响。随着刺激的重复，在一半的实验中，有节奏的后放电似乎受到了抑制。
