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舒张性心力衰竭:射血分数保留的心力衰竭

[Diastolic heart failure: heart failure with preserved ejection fraction].

作者信息

Dovjak P

机构信息

Akutgeriatrie/Remobilisation, Landeskrankenhaus Gmunden, Miller-von-Aichholz-Str. 49, 4810, Gmunden.

出版信息

Z Gerontol Geriatr. 2013 Jan;46(1):71-9; quiz 80-1. doi: 10.1007/s00391-012-0345-z.

DOI:10.1007/s00391-012-0345-z
PMID:23329260
Abstract

The prognosis for patients with diastolic heart failure--heart failure with preserved ejection fraction--has not improved in the last few decades despite improvement of prognosis for all patients with heart failure. Diastolic dysfunction is a typical finding in elderly patients with heart failure. The diagnostic process is a challenge for clinicians who are often faced with comorbidities like COPD, osteoarthritis, sarcopenia, and diabetes. Classical treatment options fail to improve patients with diastolic heart failure; thus, a comprehensive and specific treatment plan is necessary.

摘要

尽管所有心力衰竭患者的预后有所改善,但舒张性心力衰竭(射血分数保留的心力衰竭)患者的预后在过去几十年中并未得到改善。舒张功能障碍是老年心力衰竭患者的典型表现。诊断过程对临床医生来说是一项挑战,因为他们经常面临慢性阻塞性肺疾病、骨关节炎、肌肉减少症和糖尿病等合并症。传统的治疗方案无法改善舒张性心力衰竭患者的病情;因此,需要一个全面而具体的治疗计划。

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[Digitalis and theophylline: old and superfluous?].

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Renal sympathetic denervation reduces left ventricular hypertrophy and improves cardiac function in patients with resistant hypertension.肾交感神经去神经术可降低难治性高血压患者的左心室肥厚并改善心功能。
J Am Coll Cardiol. 2012 Mar 6;59(10):901-9. doi: 10.1016/j.jacc.2011.11.034.
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Heart failure with normal left ventricular ejection fraction: role of echocardiography.射血分数正常的心力衰竭:超声心动图的作用。
Curr Opin Cardiol. 2012 Mar;27(2):169-80. doi: 10.1097/HCO.0b013e32834fe8df.
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Effects of the long-term administration of nebivolol on the clinical symptoms, exercise capacity, and left ventricular function of patients with diastolic dysfunction: results of the ELANDD study.
洋地黄和茶碱:过时且多余?
Z Gerontol Geriatr. 2013 Jul;46(5):479-86; quiz 486-7. doi: 10.1007/s00391-013-0497-5.
长期服用奈必洛尔对舒张功能障碍患者临床症状、运动能力和左心室功能的影响:ELANDD 研究结果。
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Rationale and design of the treatment of preserved cardiac function heart failure with an aldosterone antagonist trial: a randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction.治疗保留心功能心力衰竭伴醛固酮拮抗剂试验的原理和设计:螺内酯治疗有症状心力衰竭和射血分数保留患者的随机对照研究。
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Exercise intolerance.运动不耐受。
Cardiol Clin. 2011 Aug;29(3):461-77. doi: 10.1016/j.ccl.2011.06.002.
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Biomarkers: optimizing treatment guidance in heart failure.生物标志物:优化心力衰竭治疗指导。
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Circ Arrhythm Electrophysiol. 2011 Oct;4(5):724-32. doi: 10.1161/CIRCEP.110.960690. Epub 2011 Jul 11.
9
Treatment of heart failure with preserved ejection fraction: have we been pursuing the wrong paradigm?射血分数保留的心力衰竭的治疗:我们是否一直追求错误的范式?
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