Satoh Masataka, Ookouchi Masayuki, Yamamoto Toshiyuki
Department of Dermatology, Fukushima Medical University School of Medicine, 1-Hikarigaoka, Fukushima, 960-1295, Japan.
J Dermatol Case Rep. 2012 Dec 31;6(4):127-9. doi: 10.3315/jdcr.2012.1122.
Proliferating pilomatricoma is a proliferative variant of pilomatricoma. Although it is considered as a benign tumor, local recurrence may occur. We report a case of a 49-year-old Japanese man with 3-year history of an asymptomatic subcutaneous tumor in the nuchal area. Histological evaluation demonstrated a cystic lesion lined by a basaloid epithelium at the periphery and filled with eosinophilic cornified material containing shadow cells in upper part of the tumor, and multilobular proliferation of basaloid cells in association with small foci of shadow cells in the remaining part. Based on these findings, the diagnosis of proliferating pilomatricoma was made. No recurrence has been observed during a 3-year follow-up.
增殖性毛母质瘤是毛母质瘤的一种增殖性变体。尽管它被认为是一种良性肿瘤，但仍可能发生局部复发。我们报告一例49岁日本男性病例，其颈部有无症状皮下肿瘤病史3年。组织学评估显示，肿瘤周边有一个由基底样上皮衬里的囊性病变，肿瘤上部充满含有影细胞的嗜酸性角化物质，其余部分为基底样细胞的多叶状增殖并伴有小灶性影细胞。基于这些发现，诊断为增殖性毛母质瘤。在3年的随访期间未观察到复发。
