Iwamuro Masaya, Kawai Yoshinari, Takata Katsuyoshi, Kawano Seiji, Yoshino Tadashi, Okada Hiroyuki, Yamamoto Kazuhide
Masaya Iwamuro, Yoshinari Kawai, Department of Gastroenterology, Onomichi Municipal Hospital, Onomichi 722-8503, Japan.
World J Gastrointest Endosc. 2013 Jan 16;5(1):34-8. doi: 10.4253/wjge.v5.i1.34.
A 69-year-old Japanese female was diagnosed with primary intestinal follicular lymphoma. Esophagogastroduodenoscopy with high-definition imaging revealed not only the typical feature of whitish polyps of up to 2 mm in diameter in the duodenal second and third portions, but also more detailed morphology, such as enlarged whitish villi and tiny whitish depositions. These findings appeared to reflect the pathological structures; infiltration of lymphoma cells into the villi were probably seen as enlargement of the villi, and the formation of lymphoid follicles were shown as opaque white spots or tiny white depositions. Thus, the above features might contribute to the distinct diagnosis of intestinal follicular lymphoma. This case indicates that routine esophagogastroduodenoscopy can visualize microsurface structures, which can be pathognomonic and help to diagnose intestinal follicular lymphoma, even without magnifying endoscopy.
一名69岁的日本女性被诊断为原发性肠道滤泡性淋巴瘤。高清成像的食管胃十二指肠镜检查不仅发现十二指肠第二和第三部分有直径达2毫米的典型白色息肉特征，还发现了更详细的形态，如增大的白色绒毛和微小的白色沉积物。这些发现似乎反映了病理结构；淋巴瘤细胞浸润到绒毛中可能表现为绒毛增大，淋巴滤泡的形成表现为不透明的白色斑点或微小的白色沉积物。因此，上述特征可能有助于肠道滤泡性淋巴瘤的明确诊断。该病例表明，常规食管胃十二指肠镜检查可以观察到微观表面结构，这些结构具有诊断特异性，有助于诊断肠道滤泡性淋巴瘤，即使不使用放大内镜也可做到。
