Ego Pharmaceuticals, Braeside, Victoria, Australia.
Australas J Dermatol. 2013 Nov;54(4):251-8. doi: 10.1111/ajd.12015. Epub 2013 Jan 18.
Atopic eczema is one of the most common skin disorders in young children and also affects adults. Staphylococcus aureus infection is the most frequent complication of atopic eczema and is involved in the worsening of the disease. Antibiotic therapy against S. aureus has been an important component of treatment for atopic eczema but there are concerns about antibiotic overuse and increasing bacterial resistance. This has led some clinicians to recommend the use of homemade remedies such as bleach baths as an adjunctive treatment for patients with infected atopic eczema, despite the fact that there have been few published studies in this area. Balancing safety concerns with efficacious treatment is of particular importance in the paediatric population. This review discusses the historical use of bleach in medicine as well as its recent use for atopic eczema. Further, the chemistry and safety of bleach as well as alternative therapies are examined.
特应性皮炎是幼儿中最常见的皮肤疾病之一,也会影响成年人。金黄色葡萄球菌感染是特应性皮炎最常见的并发症,并且会加重疾病。针对金黄色葡萄球菌的抗生素治疗一直是特应性皮炎治疗的重要组成部分,但人们担心抗生素的过度使用和细菌耐药性的增加。这导致一些临床医生建议将自制的漂白剂浴作为感染性特应性皮炎患者的辅助治疗方法,尽管在这一领域发表的研究很少。在儿科人群中,平衡安全问题和有效治疗尤为重要。这篇综述讨论了漂白剂在医学中的历史应用以及其最近在特应性皮炎中的应用。此外,还研究了漂白剂的化学性质和安全性以及替代疗法。