Rodesch G, Van Bogaert P, Mavroudakis N, Parizel P M, Martin J J, Segebarth C, Van Vyve M, Baleriaux D, Hildebrand J
Department of Neuroradiology, Hôpital Erasme, Université Libre de Bruxelles, Belgium.
Neuroradiology. 1990;32(1):26-32. doi: 10.1007/BF00593937.
Four patients with leptomeningeal metastases documented by neuroradiological examinations are reported. All had central nervous system or systemic neoplasms and showed clinical signs of carcinomatous meningitis. Gadolinium-enhanced MRI (Gd-MRI) disclosed for each patient pathological foci, allowing delineation of the extent of meningeal disease. Although non-specific, these findings, combined with the clinical context and CSF analysis, may lead to a rapid diagnosis and treatment of carcinomatous meningitis, even when malignant cells are not detected in the cerebrospinal fluid.
本文报告了4例经神经放射学检查确诊为柔脑膜转移的患者。所有患者均患有中枢神经系统或全身性肿瘤,并表现出癌性脑膜炎的临床症状。钆增强磁共振成像(Gd-MRI)显示了每位患者的病理病灶,从而能够勾勒出脑膜疾病的范围。尽管这些发现不具有特异性,但结合临床情况和脑脊液分析,即使脑脊液中未检测到恶性细胞,也可能有助于快速诊断和治疗癌性脑膜炎。