Research Centre of the University of Montreal Hospital Centre (CRCHUM), Montreal Cancer Institute, Montreal, Quebec, Canada.
J Minim Invasive Gynecol. 2013 Mar-Apr;20(2):153-9. doi: 10.1016/j.jmig.2012.11.010. Epub 2013 Jan 16.
Since 2001, many studies by different investigators have demonstrated that the fallopian tube might be at the origin of most high-grade ovarian and peritoneal serous carcinomas. Simple changes in surgical practice (ie, prophylactic bilateral salpingectomy instead of salpingo-oophorectomy) could have significant implications for death from ovarian cancer and, on the other hand, for the morbidity caused by ovariectomy (surgical menopause). In this review, we describe the new tubal carcinogenic sequence, the advantages and disadvantages of exclusive use of salpingectomy in the general population, and in cases of hereditary predisposition to ovarian cancer such as for carriers of BRCA mutation.
自 2001 年以来，许多不同研究者的研究表明，输卵管可能是大多数高级别卵巢和腹膜浆液性癌的起源。手术实践中的简单改变（即预防性双侧输卵管切除术而不是输卵管卵巢切除术）可能对卵巢癌死亡和另一方面由卵巢切除术（手术绝经）引起的发病率有重大影响。在这篇综述中，我们描述了新的输卵管致癌序列、在一般人群中单独使用输卵管切除术的优缺点，以及在遗传性易患卵巢癌的情况下，如 BRCA 突变携带者。
