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支架增强成像引导经皮冠状动脉介入治疗对中期血管造影和临床结局的影响。

Effect of StentBoost imaging guided percutaneous coronary intervention on mid-term angiographic and clinical outcomes.

机构信息

Cardiovascular Center, Korea University, Guro Hospital, 97 Guro Dong, Guro Gu, Seoul 152-703, South Korea.

出版信息

Int J Cardiol. 2013 Sep 30;168(2):1479-84. doi: 10.1016/j.ijcard.2012.12.051. Epub 2013 Jan 16.

DOI:10.1016/j.ijcard.2012.12.051
PMID:23332899
Abstract

INTRODUCTION

The gold standard for evaluating stent expansion after percutaneous coronary intervention (PCI) is intravascular ultrasound (IVUS). However, the routine use of this modality is costly and time consuming. StentBoost is a new imaging technique that improves fluoroscopy-based assessments of stent expansion. The purpose of this study was to evaluate the effect of StentBoost imaging-guided PCI on mid-term angiographic and clinical outcomes.

METHODS AND RESULTS

A total of 870 consecutive patients were recruited (mean age: 64.34 ± 11.61; men: 64.5%), all of whom underwent PCI with drug-eluting stents (DESs). The subjects were divided into a no StentBoost group (n=569 patients) and a StentBoost group (n=301 patients). The 6-month angiographic and 12-month clinical outcomes were compared between the two groups. At 1 month, clinical outcomes were similar between the two groups. At 6 months, the StentBoost group had significantly lower rates of late loss (0.32 ± 0.40 vs. 0.48 ± 0.59; p=0.005) and binary restenosis (1.2% vs. 8.3%; p=0.029) compared with the no-StentBoost group. At 12 months, StentBoost group had significantly lower the incidence of target lesion revascularization (TLR) (1.7% vs. 7%; p=0.034) and TLR-major adverse cardiac events (6% vs. 13.2%; p=0.037) compared with the no-StentBoost group.

CONCLUSION

We conclude that the routine clinical use of StentBoost during PCI can be useful, and results in better medium-term angiographic and clinical outcomes.

摘要

简介

经皮冠状动脉介入治疗(PCI)后评估支架扩张的金标准是血管内超声(IVUS)。然而,这种方式的常规使用既昂贵又费时。StentBoost 是一种新的成像技术,可改善基于荧光透视的支架扩张评估。本研究旨在评估 StentBoost 成像指导 PCI 对中期血管造影和临床结果的影响。

方法和结果

共纳入 870 例连续患者(平均年龄:64.34±11.61 岁;男性:64.5%),所有患者均接受药物洗脱支架(DES)PCI。患者分为无 StentBoost 组(n=569 例)和 StentBoost 组(n=301 例)。比较两组 6 个月的血管造影和 12 个月的临床结果。1 个月时,两组临床结果相似。6 个月时,StentBoost 组晚期管腔丢失率(0.32±0.40 比 0.48±0.59;p=0.005)和双支病变率(1.2%比 8.3%;p=0.029)显著低于无 StentBoost 组。12 个月时,StentBoost 组靶病变血运重建(TLR)发生率(1.7%比 7%;p=0.034)和 TLR-主要不良心脏事件(6%比 13.2%;p=0.037)显著低于无 StentBoost 组。

结论

我们的结论是,PCI 期间常规使用 StentBoost 可能有用,并可获得更好的中期血管造影和临床结果。

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