Wegelin I, Pane G, D'Antuono A
Boll Soc Ital Biol Sper. 1979 Sep 30;55(18):1816-22.
The developmental patterns of enzyme activities related to GMP metabolism have been investigated in chick embryo musculus complexus (m. Complexus). Guanylate phosphatase activity increases conspicuously from 18th to 21st day, guanosine phosphorylase increases on the 21st day and the guanase shows a very low activity during the whole period considered. Xanthine oxidase was always found absent. The results suggest that during the first period of incubation GMP breakdown in chick embryo m. complexus might follow a catabolic pathway, while starting from the 18th day some guanine might be converted to GMP originating a new metabolic pathway as previously suggested for AMP metabolism.
已对鸡胚复肌(复肌)中与鸟苷酸代谢相关的酶活性发育模式进行了研究。鸟苷酸磷酸酶活性在第18天至第21天显著增加,鸟苷磷酸化酶在第21天增加,而鸟嘌呤酶在所研究的整个时期内活性都非常低。始终未发现黄嘌呤氧化酶。结果表明,在孵化的第一阶段,鸡胚复肌中的鸟苷酸分解可能遵循分解代谢途径,而从第18天开始,一些鸟嘌呤可能转化为鸟苷酸,从而产生一条新的代谢途径,正如之前对腺苷酸代谢所提出的那样。