González del Pino J, Knapp K, Gómez Castresana F, Benito M
Department of Orthopaedic Surgery, Hospital La Paz, Autónoma University School of Medicine, Madrid, Spain.
Skeletal Radiol. 1990;19(3):197-202. doi: 10.1007/BF00204095.
An ischemic necrosis of the femoral head was induced in 15 mongrel adult dogs using the technique described by Gartsman et al. [10]. Five weeks later, a free vascularized rib graft was transferred into the previously induced ischemic femoral head. High resolution computed tomographic scanning was used to evaluate revascularization 4, 8 and 12 weeks after grafting. The femoral head exhibited new vessel formation throughout the study. Arterial terminal branches arising from the rib graft medullary and periosteal circulations extended beyond the rib graft, entered the head, and reached the subchondral plate. Even where the rib graft did not replenish the central core of the head, there was vascular supply from the grafted bone's vascular tree. These results suggest that a free vascularized bone graft is able to revascularize an experimentally induced ischemic femoral head necrosis.
采用Gartsman等人[10]描述的技术，在15只成年杂种犬中诱导股骨头缺血性坏死。五周后，将带血管蒂的游离肋骨移植到先前诱导的缺血性股骨头中。在移植后4周、8周和12周，使用高分辨率计算机断层扫描来评估血管再生情况。在整个研究过程中，股骨头均出现了新血管形成。来自肋骨移植髓质和骨膜循环的动脉终末分支延伸至肋骨移植之外，进入股骨头，并到达软骨下板。即使肋骨移植未能补充股骨头的中心核心区域，移植骨的血管树也能提供血管供应。这些结果表明，带血管蒂的游离骨移植能够使实验诱导的缺血性股骨头坏死实现血管再生。
