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[术前白细胞增多作为穿透性腹部创伤中腹腔内损伤的预测指标]

[Preoperative leukocytosis as a predictor of intrabdominal injury in penetrating abdominal trauma].

作者信息

Díaz-Rosales Juan de Dios, Enríquez-Domínguez Lenin, Castillo-Moreno José Romeo, Herrera-Ramírez Fernando

机构信息

Servicio de Cirugía General, Hospital General de Ciudad Juárez, División de Posgrado, Universidad Autónoma de Ciudad Juárez, Chihuahua, Mexico.

出版信息

Cir Cir. 2012 Nov-Dec;80(6):516-22.

Abstract

BACKGROUND

in Mexico, the management of abdominal penetrating trauma doesn't follow the algorithms of Trauma Center level I, because of our limitations, and laparotomies are inevitable in this context. Is possible use some grade of leukocytosis suspect in-trabdominal lesion?

METHODS

study retrospective, descriptive and analytic that inclu-ded patients with abdominal penetrating trauma that suffered exploratory laparotomy. We excluded patients' whit severe damage to soft tissues in extremities, thoracic affection, fractures, or da-mage in nervous system. We divided the patients into 2 groups: group I (therapeutic laparotomy) and group II (non-therapeutic laparotomy). Dependent variables were; age, gender, type of injury, number of lesions, peripheral lesions, time between injury and, from a laboaratory blood sample, leukocytosis mean, percentage of neutrophils, leukocytosis ≥ 12,500 /mm(3), and hemoperitoneum. We compared variables between two groups and use Pearson's χ(2) test and T-Student, and percentages as summary of measures.

RESULTS

we included 231 patients, group I with 159 patients and group II with 72 patients. Leukocytosis global was 13.2 mil/mm(3) and neutrophil range of 70.3%. 26% of patients did not have leukocytosis at arrival and evaluation, however they were laparotomized because of present peritoneal irritation. Leukocytosis ≥ 12.5 mil/mm(3) was statistically significant in patients with intrabdominal lesions (74.2% vs 27.7%, p < 0.001).

CONCLUSIONS

leukocytosis ≥ 12.5 mil/mm(3) could be an early serum marker abdominal penetrating trauma.

摘要

背景

在墨西哥,由于我们自身的局限性,腹部穿透伤的处理并不遵循一级创伤中心的算法,在此情况下剖腹手术不可避免。是否可以将某种程度的白细胞增多作为腹内病变的可疑指标呢?

方法

本研究为回顾性、描述性及分析性研究,纳入了接受剖腹探查术的腹部穿透伤患者。我们排除了四肢软组织严重损伤、胸部损伤、骨折或神经系统损伤的患者。我们将患者分为两组:第一组(治疗性剖腹手术)和第二组(非治疗性剖腹手术)。因变量包括:年龄、性别、损伤类型、损伤数量、外周损伤、受伤至采集实验室血样的时间、平均白细胞增多、中性粒细胞百分比、白细胞增多≥12,500/mm³以及腹腔积血。我们比较了两组之间的变量,并使用Pearson卡方检验和t检验,以及百分比作为测量总结。

结果

我们纳入了231例患者,第一组159例,第二组72例。总体白细胞增多为13.2万/mm³,中性粒细胞范围为70.3%。26%的患者在入院和评估时没有白细胞增多,但因存在腹膜刺激而接受了剖腹手术。腹内病变患者白细胞增多≥12.5万/mm³具有统计学意义(74.2%对27.7%,p<0.001)。

结论

白细胞增多≥12.5万/mm³可能是腹部穿透伤的早期血清标志物。

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