Moreno Joel, Pérez de Isla Leopoldo, Campos Nellys, Guinea Juan, Domínguez-Perez Laura, Saltijeral Adriana, Lennie Vera, Quezada Maribel, de Agustín Alberto, Marcos-Alberca Pedro, Mahía Patricia, García-Fernández Miguel Ángel, Macaya Carlos
Cardiovascular Imaging Unit, Hospital Carlos III Madrid, Madrid, Spain.
Echocardiography. 2013 Jul;30(6):667-71. doi: 10.1111/echo.12121. Epub 2013 Jan 22.
Current guidelines do not recommend routine assessment of right atrial volume due to the lack of standardized data. Three-dimensional wall-motion tracking (3D-WMT) is a new technology that allows us to calculate volumes without any geometric assumptions. The aim of this study was to define the indexed reference values for two-dimensional echocardiography (2D-echo) and 3D-WMT in adult healthy population and to assess the intermethod, intra- and interobserver agreement.
Prospective study. Nonselected healthy subjects were enrolled. Every patient underwent a 2D-echo and a 3D-WMT examination. 2D-echo right atrial volume was obtained by using the area-length method (A-L) from four- and two-chamber view. 3D-echo volumes were assessed by 3D-WMT. Values were indexed by the patient's body surface area.
Sixty consecutive healthy subjects were enrolled. Mean age was 57 ± 12-years old and 27 patients (45%) were male. Average indexed right atrial volume obtained by 2D-echo and 3D-echo was 16.76 ± 8.15 mL/m(2) and 19.05 ± 6.87 mL/m(2) , respectively. Univariate linear regression analysis between 2D-echo and 3D-echo right atrial volumes shows a weak correlation between right atrial volume obtained with 2D-echo compared with 3D-WMT (r = 0.29, CI 95% 0.029-0.66, P = 0.033). The agreement analysis shows a similar result (intraclass correlation coefficient [ICC] = 0.28). The intra- and interobserver agreement analysis showed a better agreement when using 3D-WMT.
This is the first study that reports the reference indexed right atrial volume values by means of 2D-echo and 3D-echo in healthy population. 3D-WMT is a feasible and reproducible method to determine right atrial volume.
由于缺乏标准化数据，目前的指南不建议对右心房容积进行常规评估。三维壁运动追踪（3D-WMT）是一项新技术，可让我们在无需任何几何假设的情况下计算容积。本研究的目的是确定成人健康人群二维超声心动图（2D-echo）和3D-WMT的指数化参考值，并评估不同方法之间、观察者内及观察者间的一致性。
前瞻性研究。纳入未经过筛选的健康受试者。每位患者均接受2D-echo和3D-WMT检查。通过面积-长度法（A-L）从四腔心和两腔心视图获取2D-echo右心房容积。通过3D-WMT评估3D-echo容积。数值用患者的体表面积进行指数化。
连续纳入60名健康受试者。平均年龄为57±12岁，27名患者（45%）为男性。通过2D-echo和3D-echo获得的平均指数化右心房容积分别为16.76±8.15 mL/m²和19.05±6.87 mL/m²。2D-echo和3D-echo右心房容积之间的单变量线性回归分析显示，与3D-WMT相比，2D-echo获得的右心房容积之间存在弱相关性（r = 0.29，95%CI 0.029 - 0.66，P = 0.033）。一致性分析显示了类似结果（组内相关系数[ICC] = 0.28）。观察者内及观察者间一致性分析显示，使用3D-WMT时一致性更好。
这是第一项报告健康人群中通过2D-echo和3D-echo得出的参考指数化右心房容积值的研究。3D-WMT是一种可行且可重复的确定右心房容积的方法。
