Clin Pharmacol Ther. 2013 Feb;93(2):133-5. doi: 10.1038/clpt.2012.229.
Every day it is easy to find news articles detailing the impact of drug shortages on patients. Where this was once only a concern of patients with rare, orphan diseases, it is now the concern of patients receiving even the most common chemotherapeutic regimens, the most efficacious antimicrobial therapy, or even the most rapid-acting analgesics, largely as a result of manufacturing quality problems. Unfortunately for many of these patients, there are no efficacious alternatives.
每天都很容易找到详细报道药品短缺对患者影响的新闻文章。曾经，这只是罕见病、孤儿病患者所关心的问题，但现在，即使是接受最常见化疗方案、最有效的抗菌治疗，甚至是起效最快的镇痛药的患者，也开始关注这一问题，主要是因为生产质量问题。对于这些患者中的许多人来说，不幸的是，没有有效的替代药物。
