Bradford Leslie, Goodman Annekathryn
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA 02114, USA.
Clin Obstet Gynecol. 2013 Mar;56(1):76-87. doi: 10.1097/GRF.0b013e31828237ac.
Cervical cancer is both preventable and curable, yet it remains one of the leading causes of mortality in women worldwide. Approximately 88% of cervical cancer cases are diagnosed in low-resource countries, yet very few resources are allocated to prevention and treatment programs. In fact, it is estimated that only 5% of women in low-resources countries are screened appropriately for cervical cancer. Cytology-based programs are not feasible because of lack of healthcare infrastructure and cost, thus alternative methods of cancer screening, such as visual inspection with acetic acid and HPV-DNA testing, have been intensively studied and are reviewed in this article.
宫颈癌既是可预防的,也是可治愈的,但它仍然是全球女性死亡的主要原因之一。大约88%的宫颈癌病例在资源匮乏的国家被诊断出来,但分配给预防和治疗项目的资源却非常少。事实上,据估计,资源匮乏国家只有5%的女性接受了适当的宫颈癌筛查。基于细胞学的项目由于缺乏医疗基础设施和成本而不可行,因此,诸如醋酸目视检查和人乳头瘤病毒DNA检测等癌症筛查替代方法已得到深入研究,并在本文中进行了综述。