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使用调整后的分位数距离函数比较男女的出生体重差异。

Differences in birth weight by sex using adjusted quantile distance functions.

机构信息

Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

出版信息

Stat Med. 2013 Jul 30;32(17):2962-70. doi: 10.1002/sim.5744. Epub 2013 Jan 22.

Abstract

Herein, we report results from a study of birth weight distribution among boys and girls born in Norway in 2008. As our primary interest was to detect differences in the variability between the two sexes, we used the quantile distance function to describe the difference between two distribution functions. We used an adjusted version of the quantile function to look into the relation of sex differences in birth weight conditioned on maternal age, gestational age, preeclampsia, maternal diabetes type 1, maternal smoking status, and parity. At term (⩾37 weeks of gestation), boys showed a greater variability in birth weight than did girls, and these differences were maintained in the adjusted model. We also found that maternal age and maternal smoking habits influenced both sexes equally, whereas gestational age, preeclampsia, maternal diabetes type 1, and parity influenced one sex more than the other. The adjusted quantile distance function proved efficient in analyzing and demonstrating how covariates influence sex differences in birth weight.

摘要

在此,我们报告了对 2008 年在挪威出生的男婴和女婴的出生体重分布进行的一项研究结果。由于我们的主要兴趣是检测两性之间的可变性差异,因此我们使用分位数距离函数来描述两个分布函数之间的差异。我们使用了分位数函数的调整版本,研究了在考虑母亲年龄、胎龄、子痫前期、1 型糖尿病、母亲吸烟状况和产次的情况下,出生体重的性别差异之间的关系。在足月(≥37 周妊娠)时,男孩的出生体重比女孩的出生体重变化更大,而且这些差异在调整后的模型中仍然存在。我们还发现,母亲年龄和母亲吸烟习惯对两性的影响相同,而胎龄、子痫前期、1 型糖尿病和产次对一种性别比另一种性别的影响更大。调整后的分位数距离函数在分析和演示协变量如何影响出生体重的性别差异方面非常有效。

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