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加纳北部随机生物质炊具干预的健康影响。

Health impacts of a randomized biomass cookstove intervention in northern Ghana.

机构信息

Colorado School of Public Health, Aurora, USA.

Navrongo Health Research Centre, Navrongo, Ghana.

出版信息

BMC Public Health. 2021 Dec 4;21(1):2211. doi: 10.1186/s12889-021-12164-y.

DOI:10.1186/s12889-021-12164-y
PMID:34863138
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8642932/
Abstract

BACKGROUND

Household air pollution (HAP) from cooking with solid fuels has adverse health effects. REACCTING (Research on Emissions, Air quality, Climate, and Cooking Technologies in Northern Ghana) was a randomized cookstove intervention study that aimed to determine the effects of two types of "improved" biomass cookstoves on health using self-reported health symptoms and biomarkers of systemic inflammation from dried blood spots for female adult cooks and children, and anthropometric growth measures for children only.

METHODS

Two hundred rural households were randomized into four different cookstove groups. Surveys and health measurements were conducted at four time points over a two-year period. Chi-square tests were conducted to determine differences in self-reported health outcomes. Linear mixed models were used to assess the effect of the stoves on inflammation biomarkers in adults and children, and to assess the z-score deviance for the anthropometric data for children.

RESULTS

We find some evidence that two biomarkers of oxidative stress and inflammation, serum amyloid A and C-reactive protein, decreased among adult primary cooks in the intervention groups relative to the control group. We do not find detectable impacts for any of the anthropometry variables or self-reported health.

CONCLUSIONS

Overall, we conclude that the REACCTING intervention did not substantially improve the health outcomes examined here, likely due to continued use of traditional stoves, lack of evidence of particulate matter emissions reductions from "improved" stoves, and mixed results for HAP exposure reductions.

CLINICAL TRIAL REGISTRY

ClinicalTrials.gov (National Institutes of Health); Trial Registration Number: NCT04633135 ; Date of Registration: 11 November 2020 - Retrospectively registered. URL: https://clinicaltrials.gov/ct2/show/NCT04633135?term=NCT04633135&draw=2&rank=1.

摘要

背景

烹饪固体燃料产生的家用空气污染(HAP)对健康有不良影响。REACCTING(加纳北部排放、空气质量、气候和烹饪技术研究)是一项随机炊具干预研究,旨在通过女性成年厨师和儿童的自我报告健康症状和系统炎症生物标志物以及仅针对儿童的人体测量生长指标,确定两种“改良”生物质炊具对健康的影响。

方法

200 户农村家庭被随机分为四组不同的炊具组。在两年期间进行了四次调查和健康测量。进行了卡方检验以确定自我报告的健康结果差异。线性混合模型用于评估炉子对成人和儿童炎症生物标志物的影响,并评估儿童人体测量数据的 z 分数偏差。

结果

我们发现一些证据表明,与对照组相比,干预组中两种氧化应激和炎症的生物标志物,血清淀粉样蛋白 A 和 C 反应蛋白,在成年主要厨师中有所下降。我们没有发现任何人体测量变量或自我报告健康有可检测到的影响。

结论

总的来说,我们得出的结论是,REACCTING 干预并没有显著改善这里检查的健康结果,这可能是由于继续使用传统炉灶、“改良”炉灶减少颗粒物排放的证据不足以及 HAP 暴露减少的结果喜忧参半。

临床试验注册

ClinicalTrials.gov(美国国立卫生研究院);试验注册编号:NCT04633135;注册日期:2020 年 11 月 11 日-追溯注册。网址:https://clinicaltrials.gov/ct2/show/NCT04633135?term=NCT04633135&draw=2&rank=1。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e679/8642932/cf099e65661e/12889_2021_12164_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e679/8642932/5eacb812dd48/12889_2021_12164_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e679/8642932/13322dfa367e/12889_2021_12164_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e679/8642932/2ed88ed45aa6/12889_2021_12164_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e679/8642932/d7a15b0bd737/12889_2021_12164_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e679/8642932/5c0cb62205b3/12889_2021_12164_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e679/8642932/cf099e65661e/12889_2021_12164_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e679/8642932/5eacb812dd48/12889_2021_12164_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e679/8642932/13322dfa367e/12889_2021_12164_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e679/8642932/2ed88ed45aa6/12889_2021_12164_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e679/8642932/d7a15b0bd737/12889_2021_12164_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e679/8642932/5c0cb62205b3/12889_2021_12164_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e679/8642932/cf099e65661e/12889_2021_12164_Fig6_HTML.jpg

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