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双吻合器痔上黏膜环切术治疗痔脱垂:一项多中心、前瞻性、非随机试验

Double PPH technique for hemorrhoidal prolapse: a multicentric, prospective, and nonrandomized trial.

作者信息

Braini A, Narisetty P, Favero A, Calandra S, Calandra A, Caponnetto F, Digito F, Da Pozzo F, Marcotti E, Porebski E, Rovedo S, Terrosu G, Torricelli L, Stuto A

机构信息

1U.O. Chirurgia 2, Az. Ospedaliera S. Maria degli Angeli, Pordenone, Italy.

出版信息

Surg Innov. 2013 Dec;20(6):553-8. doi: 10.1177/1553350612472988. Epub 2013 Jan 20.

Abstract

INTRODUCTION

Longo's technique (or PPH technique) is well known worldwide. Meta-analysis suggests that the failure due to persistence or recurrence is close to 7.7%. One of the reasons for the recurrence is the treatment of the advanced hemorrhoidal prolapse with a single stapling device, which is not enough to resect the appropriate amount of prolapse.

MATERIALS AND METHODS

We describe the application of "Double PPH Technique" (D-PPH) to treat large hemorrhoidal prolapses. We performed a multicentric, prospective, and nonrandomized trial from July 2008 to July 2009, wherein 2 groups of patients with prolapse and hemorrhoids were treated with a single PPH or a D-PPH. Results were compared. The primary outcome was evaluation of safety and efficacy of the D-PPH procedure in selected patients with large hemorrhoidal prolapse.

RESULTS

In all, 281 consecutive patients suffering from hemorrhoidal prolapse underwent surgery, of whom 74 were assigned intraoperatively to D-PPH, whereas 207 underwent single PPH. Postoperative complications were 5% in both groups (P = .32), in particular: postoperative major bleeding 3.0% in PPH versus 4.1% D-PPH (P = .59); pain 37.9 % PPH versus 27.3% D-PPH (mean visual analog scale [VAS] = 2.5 vs 2.9, respectively; P = .72); and fecal urgency 2.1% PPH versus 5.7% D-PPH (P = .8). Persistence of hemorrhoidal prolapse at 12-month follow-up was 3.7% in the PPH group versus 5.9% in the D-PPH group (P = .5).

CONCLUSIONS

Our data support the hypothesis that an accurate intraoperative patient selection for single (PPH) or double (D-PPH) stapled technique will lower in a significant way the incidence of recurrence after Longo's procedure for hemorrhoidal prolapse.

摘要

引言

龙氏技术(或吻合器痔上黏膜环切术)在全球范围内广为人知。荟萃分析表明,因持续存在或复发导致的失败率接近7.7%。复发的原因之一是使用单个吻合器装置治疗晚期痔脱垂,这不足以切除适量的脱垂组织。

材料与方法

我们描述了“双吻合器痔上黏膜环切术”(D-PPH)治疗巨大痔脱垂的应用。我们于2008年7月至2009年7月进行了一项多中心、前瞻性、非随机试验,其中两组痔脱垂患者分别接受单次PPH或D-PPH治疗。对结果进行了比较。主要结局是评估D-PPH手术在选定的巨大痔脱垂患者中的安全性和有效性。

结果

共有281例连续的痔脱垂患者接受了手术,其中74例术中被分配接受D-PPH,而207例接受单次PPH。两组术后并发症发生率均为5%(P = 0.32),具体如下:术后大出血,PPH组为3.0%,D-PPH组为4.1%(P = 0.59);疼痛,PPH组为37.9%,D-PPH组为27.3%(平均视觉模拟评分[VAS]分别为2.5和2.9;P = 0.72);以及便急,PPH组为2.1%,D-PPH组为5.7%(P = 0.8)。PPH组在12个月随访时痔脱垂持续存在的比例为3.7%,D-PPH组为5.9%(P = 0.5)。

结论

我们的数据支持这样一种假设,即术中准确选择单次(PPH)或双次(D-PPH)吻合器技术的患者,将显著降低龙氏痔脱垂手术后的复发率。

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