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细针硬化疗法作为一种非寄生虫性脾囊肿的新有效治疗方法:病例系列。

Fine needle sclerotherapy as a new effective therapeutic approach for nonparasitic splenic cysts: a case series.

机构信息

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

出版信息

Dig Liver Dis. 2013 Jul;45(7):595-9. doi: 10.1016/j.dld.2012.12.008. Epub 2013 Jan 20.

Abstract

BACKGROUND

Nonparasitic splenic cysts are rare. Until now, surgical intervention has been the standard therapy of symptomatic splenic cysts.

AIMS

We herein present a retrospective analysis of an approach using percutaneous ultrasound-guided fine needle aspiration and sclerotherapy.

METHODS

Out of 88,151 ultrasound reports, we identified 138 patients who presented with splenic cysts. A single splenic cyst was found in 88% (mean size 28.9 mm). Twelve patients underwent percutaneous therapy of symptomatic splenic cysts. They were younger, had larger splenic cysts and more often cyst internal echoes than the 126 untreated patients (all p < 0.0001).

RESULTS

Initial sclerotherapy was performed with polidocanol 1% in 9 patients and with NaCl 10% in 2 patients. One hemorrhagic cyst was only purged. Serious adverse events were not noted. Eight patients had to undergo 1-11 further percutaneous cyst therapies. 15 of these 30 reinterventions were cyst aspiration therapies, only, and 11 of them were sclerotherapies with NaCl 10%. Four patients were readmitted to hospital for cyst retreatment. After 57 ± 43 months of follow-up, cyst size significantly decreased (p < 0.0001). Only two patients had a complicated course of cyst therapy.

CONCLUSIONS

Percutaneous ultrasound-guided sclerotherapy is a new approach for symptomatic splenic cysts. In most patients, cyst size and symptoms can be significantly reduced during one hospital stay.

摘要

背景

非寄生虫性脾囊肿较为罕见。到目前为止,手术干预一直是治疗有症状脾囊肿的标准疗法。

目的

我们在此回顾性分析了一种经皮超声引导下细针抽吸和硬化治疗的方法。

方法

在 88151 份超声报告中,我们确定了 138 例有脾囊肿表现的患者。88%(平均大小 28.9mm)的患者为单发脾囊肿。12 例有症状的脾囊肿患者接受了经皮治疗。与 126 例未治疗的患者相比,这些患者年龄更小,脾囊肿更大,且更常出现囊肿内部回声(均<0.0001)。

结果

9 例患者初始硬化治疗采用 1%聚多卡醇,2 例患者采用 10%NaCl。1 例出血性囊肿仅被冲洗。未发生严重不良事件。8 例患者需要进行 1-11 次经皮囊肿治疗。这 30 次再介入中有 15 次仅为囊肿抽吸治疗,其中 11 次为 10%NaCl 硬化治疗。4 例患者因囊肿再次治疗而住院。在 57±43 个月的随访后,囊肿大小显著减小(<0.0001)。只有 2 例患者的囊肿治疗过程较为复杂。

结论

经皮超声引导下硬化治疗是一种治疗有症状脾囊肿的新方法。在大多数患者中,单次住院期间可显著缩小囊肿大小并减轻症状。

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