Department of Medicine, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Curr Opin Clin Nutr Metab Care. 2013 Mar;16(2):202-8. doi: 10.1097/MCO.0b013e32835dbc54.
This review evaluates whether improvements have occurred in the value of predictive equations for use in designing nutritional therapeutic regimens in the ICU. The report also seeks to determine whether emerging strategies for nutrition therapy in the ICU change the need for an accurate measurement of energy requirements by indirect calorimetry.
Predictive equations remain problematic for use in the critically ill patient. Inaccuracy of predictive equations introduces error in the design of a nutritional therapy regimen. The epidemic of obesity renders the calculations of requirements by predictive equations increasingly inaccurate at extremes of BMI. Certain patient populations appear to be hypometabolic, contradicting the traditional notion that critical illness increases energy expenditure. More recent data indicates that determination of which patients benefit from nutritional therapy may be based both on assessment of nutrition risk and delivery of sufficient nutrition therapy.
The role of indirect calorimetry in the ICU should be expected to increase in the near future, as predictive equations may be too inaccurate to identify the appropriate goals of nutrition therapy.
本综述评估了在 ICU 中设计营养治疗方案时,预测方程的价值是否有所提高。该报告还试图确定 ICU 中新兴的营养治疗策略是否改变了对间接测热法准确测量能量需求的需求。
预测方程在危重病患者中的应用仍然存在问题。预测方程的不准确性会导致营养治疗方案的设计出现错误。肥胖症的流行使得预测方程计算的需求在 BMI 极端值处越来越不准确。某些患者群体似乎代谢较低,这与传统观念即危重病会增加能量消耗相矛盾。最近的数据表明,确定哪些患者受益于营养治疗可能基于营养风险评估和提供足够的营养治疗。
在不久的将来,间接测热法在 ICU 中的作用预计将会增加,因为预测方程可能不够准确,无法确定营养治疗的适当目标。