Department of Neuroscience, Medical University of South Carolina, Charleston, SC, USA.
Top Stroke Rehabil. 2013 Jan-Feb;20(1):68-77. doi: 10.1310/tsr2001-68.
Motor impairment, dysphagia, aphasia, and visual impairment are common disabling residual deficits experienced by stroke survivors. Recently, many novel rehabilitative modalities have been investigated for their potential to ameliorate such deficits and to improve functional outcomes. Noninvasive brain stimulation techniques, such as transcranial direct current stimulation (tDCS), have emerged as a promising tool to facilitate stroke recovery. tDCS can alter cortical excitability to induce brain plasticity by modulating the lesioned, contralesional, or bilateral hemispheres with various stimulation modalities. Along with peripheral therapies, tDCS can lead to subsequent sustained behavioral and clinical gains in patients with stroke. In this review, we summarize characteristics of tDCS (method of stimulation, safety profile, and mechanism) and its application in the treatment of various stroke-related deficits, and we highlight future directions for tDCS in this capacity.
运动障碍、吞咽困难、失语症和视力障碍是中风幸存者常见的致残性残留缺陷。最近，许多新的康复治疗方法已经被研究，以评估它们改善这些缺陷和提高功能结果的潜力。非侵入性脑刺激技术，如经颅直流电刺激（tDCS），已成为一种很有前途的工具，可以促进中风康复。tDCS 通过改变刺激方式调节损伤侧、对侧或双侧半球，可以改变皮质兴奋性，诱导大脑可塑性。与外周治疗相结合，tDCS 可以在中风患者中产生后续的持续行为和临床获益。在这篇综述中，我们总结了 tDCS 的特点（刺激方法、安全性和机制）及其在治疗各种中风相关缺陷中的应用，并强调了 tDCS 在这方面的未来发展方向。
