Kocahasan Melike, Stockbridge Melissa D, Stilling Joan, Utianski Rene L, Sebastian Rajani, Keser Zafer
School of Medicine, Koc University, Istanbul 34450, Turkey.
Department of Neurology, Johns Hopkins University, Baltimore, MD 21287, USA.
Medicina (Kaunas). 2025 Mar 29;61(4):627. doi: 10.3390/medicina61040627.
: Stroke is a leading cause of disability worldwide. Recent studies have suggested the feasibility and potential utility of remotely supervised transcranial direct current stimulation (RS-tDCS) to improve different types of impairments in various neurological conditions. This scoping review provides a critical appraisal of RS-tDCS as an adjunct therapy to enhance recovery after stroke. : A comprehensive literature review was systematically conducted using PubMed through Nested Knowledge software. A supplementary search was conducted in Google Scholar. Two independent authors screened and identified related studies investigating RS-tDCS in patients with stroke from inception to February 2025. : Studies showed that RS-tDCS was safe, with only mild side effects. Additionally, it was feasible, with high adherence rates likely due to ease of use. Regarding efficacy, RS-tDCS preliminarily yielded improvements in upper- and lower-limb motor functions and increased language and cognitive performance. However, the studies were underpowered and heterogeneous, limiting generalization of findings. : RS-tDCS is safe and feasible, affording beneficial effects in the motor, language, and cognitive functions of patients with post-stroke impairments. RS-tDCS has the potential to improve access and reduce disparities for post-stroke experimental treatments. However, adequately powered randomized trials are needed to further investigate the efficacy.
中风是全球残疾的主要原因。最近的研究表明,远程监督经颅直流电刺激(RS-tDCS)在改善各种神经疾病的不同类型损伤方面具有可行性和潜在效用。本范围综述对RS-tDCS作为中风后促进恢复的辅助疗法进行了批判性评估。:通过嵌套知识软件使用PubMed系统地进行了全面的文献综述。在谷歌学术上进行了补充搜索。两位独立作者筛选并确定了从开始到2025年2月调查中风患者RS-tDCS的相关研究。:研究表明,RS-tDCS是安全的,只有轻微的副作用。此外,它是可行的,由于使用方便,依从率很高。关于疗效,RS-tDCS初步改善了上肢和下肢的运动功能,并提高了语言和认知表现。然而,这些研究的样本量不足且具有异质性,限制了研究结果的推广。:RS-tDCS是安全可行的,对中风后损伤患者的运动、语言和认知功能具有有益影响。RS-tDCS有可能改善中风后实验性治疗的可及性并减少差异。然而,需要有足够样本量的随机试验来进一步研究其疗效。
Medicina (Kaunas). 2025-3-29
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