Moss R L, Ryan J A
Virginia Mason Medical Center, Seattle, Washington.
Am J Surg. 1990 May;159(5):514-7. doi: 10.1016/s0002-9610(05)81259-0.
The records of 51 patients diagnosed with enterovesical fistulas at Virginia Mason Medical Center from 1974 to 1988 were reviewed. Diverticulitis (41%), Crohn's disease (17%), and colorectal cancer (16%) were the major causes. In 50 of 51 patients, the diagnosis was made on the basis of the clinical history and the urine culture. Radiologic and endoscopic studies failed to identify the fistula in 20%, though all were confirmed at operation or autopsy. In four of eight patients with fistulas secondary to colorectal cancer, malignancy was not diagnosed preoperatively. Operation was performed in 84% of the patients. One-stage resection of the bowel was performed in 66% of patients with the intent of removing the fistula. The complication rate was 8% with no deaths. All multi-stage procedures were performed for fistulas complicated by abscess or bowel obstruction. There were two postoperative deaths in patients with metastatic cancer undergoing palliative diversion. All eight patients treated by diverting colostomy had persistent fistulas and urinary sepsis. All eight patients treated with antibiotics but without operation were free of complications of the fistula until death from other causes. Enterovesical fistula is a clinical diagnosis. Preoperative studies should be used to delineate the bowel disease and search for malignancy rather than to see the fistula, which is clinically apparent. One-stage resection of the involved bowel is the procedure of choice in the absence of abscess or bowel obstruction. When resection is not feasible, medical management with antibiotics is preferable to colostomy.
对1974年至1988年在弗吉尼亚梅森医疗中心诊断为肠膀胱瘘的51例患者的记录进行了回顾。憩室炎(41%)、克罗恩病(17%)和结直肠癌(16%)是主要病因。51例患者中有50例根据临床病史和尿培养做出诊断。放射学和内镜检查在20%的患者中未能发现瘘管,不过所有瘘管均在手术或尸检时得到证实。在8例继发于结直肠癌的瘘管患者中,有4例术前未诊断出恶性肿瘤。84%的患者接受了手术。66%的患者进行了一期肠切除,目的是切除瘘管。并发症发生率为8%,无死亡病例。所有多期手术均针对并发脓肿或肠梗阻的瘘管进行。接受姑息性分流的转移性癌症患者中有2例术后死亡。所有8例接受结肠造口术治疗的患者均有持续性瘘管和尿脓毒症。所有8例接受抗生素治疗但未手术的患者在因其他原因死亡前均未出现瘘管并发症。肠膀胱瘘是一种临床诊断。术前检查应用于明确肠道疾病并寻找恶性肿瘤,而非用于观察临床上已很明显的瘘管。在没有脓肿或肠梗阻的情况下,一期切除受累肠段是首选的手术方式。当无法进行切除时,使用抗生素的药物治疗优于结肠造口术。