Saksø H, Jakobsen T, Saksø M, Baas J, Jakobsen Ss, Soballe K
Department of Orthopaedics, Aarhus University Hospital, Norrebrogade 44, Aarhus, Denmark.
Open Orthop J. 2013;7:1-7. doi: 10.2174/1874325001307010001. Epub 2013 Jan 9.
Implant surface treatments that improve early osseointegration may prove useful in long-term survival of uncemented implants. We investigated Acid Etching and Plasma Cleaning on titanium implants.
In a randomized, paired animal study, four porous coated Ti implants were inserted into the femurs of each of ten dogs. PC (Porous Coating; control)PC+PSHA (Plasma Sprayed Hydroxyapatite; positive control)PC+ET (Acid Etch)PC+ET+PLCN (Plasma Cleaning) After four weeks mechanical fixation was evaluated by push-out test and osseointegration by histomorphometry.
The PSHA-coated implants were better osseointegrated than the three other groups on outer surface implant porosity (p<0.05) while there was no statistical difference in deep surface implant porosity when compared with nontreated implant. Within the deep surface implant porosity, there was more newly formed bone in the control group compared to the ET and ET+PCLN groups (p<0.05). In all compared groups, there was no statistical difference in any biomechanical parameter.
In terms of osseointegration on outer surface implant porosity PC+PSHA was superior to the other three groups. Neither the acid etching nor the plasma cleaning offered any advantage in terms of implant osseointegration. There was no statistical difference in any of the biomechanical parameters among all groups in the press-fit model at 4 weeks of evaluation time.
能够改善早期骨结合的种植体表面处理方法可能对非骨水泥型种植体的长期存活有益。我们研究了钛种植体的酸蚀处理和等离子体清洁处理。
在一项随机配对动物研究中,将四颗多孔涂层钛种植体植入十只狗每只的股骨中。PC(多孔涂层;对照组)PC + PSHA(等离子喷涂羟基磷灰石;阳性对照组)PC + ET(酸蚀)PC + ET + PLCN(等离子体清洁)四周后,通过推出试验评估机械固定情况,并通过组织形态计量学评估骨结合情况。
在种植体外表面孔隙率方面,PSHA涂层种植体的骨结合情况优于其他三组(p < 0.05),而与未处理的种植体相比,在种植体深表面孔隙率方面无统计学差异。在深表面孔隙率范围内,与ET组和ET + PLCN组相比,对照组有更多新形成的骨(p < 0.05)。在所有比较组中,任何生物力学参数均无统计学差异。
就种植体外表面孔隙率的骨结合而言,PC + PSHA优于其他三组。酸蚀处理和等离子体清洁处理在种植体骨结合方面均未显示出任何优势。在评估时间为四周的压配模型中,所有组的任何生物力学参数均无统计学差异。