[抗菌表面活性剂对小鼠胸腺依赖性抗原免疫反应的影响]
[Effect of antimicrobial surface-active agents on the immune response to thymus-dependent antigen in mice].
作者信息
Krivoshein Iu S, Shatrov V A
出版信息
Antibiot Khimioter. 1990 Jan;35(1):35-7.
PMID:2334243
Abstract
The study showed that miramystin, a cationi surfactant, was an immunostimulant inducing an increase in humoral and cellular immunity in response to sheep red blood cells. The observed dose-dependent stimulating effect of miramystin on antibody production and development of DTH recommends its use as an immunologic adjuvant in the laboratory practice. It also indicated to the prospects in investigation of immunologic adjuvant properties of other preparations belonging to surface-active substances.
摘要
该研究表明，阳离子表面活性剂米拉美斯汀是一种免疫刺激剂，可诱导针对绵羊红细胞的体液免疫和细胞免疫增加。观察到的米拉美斯汀对抗体产生和迟发型超敏反应发展的剂量依赖性刺激作用，推荐其在实验室实践中用作免疫佐剂。这也指出了研究其他属于表面活性物质的制剂免疫佐剂特性的前景。
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