[非甾体抗炎药的免疫调节特性]
[Immunomodulating properties of non-steroidal anti-inflammatory drugs].
作者信息
Evstropov A N, Gritsenko L N, Orolovskaia I A, Saratikov A S, Prishchep T P, Iavorovskaia V E
出版信息
Biull Eksp Biol Med. 1991 Jan;111(1):55-7.
There has been studied the influence of a number of nonsteroidal antiinflammatory agents (NSAID ) on the humoral immune response of mice in immunization with erythrocytic and viral antigen. It has been found out that NSAID have immunomodulating effect, stimulating humoral immune response (4-iodantipyrine, 4-bromantipyrine) or suppressing it (butadione, sodium salicylate). Apparently the mechanism of NSAID ++ immunostimulating effect is related to the inhibition of T-suppressors ++ function by the latter ones.
已经研究了多种非甾体抗炎药（NSAID）对小鼠在用红细胞和病毒抗原免疫时体液免疫反应的影响。已经发现，NSAID具有免疫调节作用，可刺激体液免疫反应（4-碘安替比林、4-溴安替比林）或抑制它（布他酮、水杨酸钠）。显然，NSAID的免疫刺激作用机制与后者对T抑制细胞功能的抑制有关。
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