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监测透析结局(MONDO)倡议。

The MONitoring Dialysis Outcomes (MONDO) initiative.

机构信息

Renal Research Institute, New York, NY 10128, USA.

出版信息

Blood Purif. 2013;35(1-3):37-48. doi: 10.1159/000345179. Epub 2013 Jan 22.

DOI:10.1159/000345179
PMID:23343545
Abstract

BACKGROUND

Systematic collection and analysis of global hemodialysis patient data may help to improve patient outcomes.

METHODS

The MONitoring Dialysis Outcomes (MONDO) initiative comprises data from eight dialysis providers worldwide. Data are combined into one repository. Extensive procedures are employed to merge data across countries and providers.

RESULTS

The MONDO database comprises longitudinal data of currently 128,000 hemodialysis patients from 26 countries on five continents. Here we report data from 62,345 incident hemodialysis patients. We found lower catheter rates in South-East Asia and Australia, lower hemoglobin levels in South-East Asia, and a higher prevalence of diabetes in North America. Longitudinal analyses suggest that there is a decline in interdialytic weight gain and serum phosphorus and an increasing neutrophil-to-lymphocyte ratio before death in all regions studied.

CONCLUSIONS

While organizationally lean and low-cost, MONDO is the largest global dialysis database initiative to date, with a particular focus on high longitudinal data density and geographical diversity.

摘要

背景

系统地收集和分析全球血液透析患者数据,可能有助于改善患者预后。

方法

MONitoring Dialysis Outcomes(MONDO)计划包括来自全球 8 家透析供应商的数据。这些数据被整合到一个数据库中。采用了广泛的程序来合并不同国家和供应商的数据。

结果

MONDO 数据库包含了来自五大洲 26 个国家的 128000 名正在进行血液透析患者的纵向数据。在这里,我们报告了来自 62345 名新开始血液透析的患者的数据。我们发现东南亚和澳大利亚的导管使用率较低,东南亚的血红蛋白水平较低,而北美的糖尿病患病率较高。纵向分析表明,在所有研究的地区,透析间期体重增加、血清磷和中性粒细胞与淋巴细胞比值在死亡前都呈下降趋势。

结论

尽管 MONDO 在组织上精简且成本低,但它是迄今为止最大的全球透析数据库计划,特别注重高纵向数据密度和地理多样性。

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