Calice-Silva Viviane, Hussein Rasha, Yousif Dalia, Zhang Hanjie, Usvyat Len, Campos Ludimila G, von Gersdorff Gero, Schaller Mathias, Marcelli Danielle, Grassman Aileen, Etter Michael, Xu Xiaoqi, Kotanko Peter, Pecoits-Filho Roberto
School of Medicine, Pontificia Universidade Católica do Paraná, Curitiba, Brazil.
Blood Purif. 2015;39(1-3):125-36. doi: 10.1159/000368980. Epub 2015 Jan 20.
The number of patients receiving renal replacement therapy (RRT) increases annually and worldwide. Differences in the RRT incidence, prevalence, and modality vary between regions and countries for reasons yet to be clarified.
Gain a better understanding of the association between hemodialysis (HD)-related variables and general population global health indicators.
The present study included prevalent HD patients from 27 countries/regions from the monitoring dialysis outcomes (MONDO) database from 2006-2011. Global population health indicators were obtained from the 2014 World Health Organization report and the Human Development Index from the Human Development Report Office 2014. The Spearman rank test was used to assess the correlations between population social economic indicators and HD variables.
A total of 84,796 prevalent HD patients were included. Their mean age was 63 (country mean 52-71), and 60% were males (country mean 52-85%). Significant correlations were found between HD demographic clusters and population education, wealth, mortality, and health indicators. The cluster of nutrition and inflammation variables were also highly correlated with population mortality, wealth, and health indicators. Finally, cardiovascular, fluid management, and dialysis adequacy clusters were associated with education, wealth, and health care resource indicators.
We identified socioeconomic indicators that were correlated with dialysis variables. This hypothesis-generating study may be helpful in the analysis of how global health indicators may interfere with access to HD, treatment provision, dialytic treatment characteristics, and outcomes.
全球范围内，接受肾脏替代治疗（RRT）的患者数量逐年增加。RRT的发病率、患病率和治疗方式在不同地区和国家存在差异，原因尚待阐明。
更好地理解血液透析（HD）相关变量与全球人口健康指标之间的关联。
本研究纳入了2006年至2011年监测透析结果（MONDO）数据库中来自27个国家/地区的HD现患患者。全球人口健康指标来自2014年世界卫生组织报告，人类发展指数来自2014年人类发展报告办公室。采用Spearman秩和检验评估人口社会经济指标与HD变量之间的相关性。
共纳入84,796例HD现患患者。他们的平均年龄为63岁（各国平均年龄为52 - 71岁），60%为男性（各国平均比例为52 - 85%）。HD人口统计学分组与人口教育、财富、死亡率和健康指标之间存在显著相关性。营养和炎症变量分组也与人口死亡率、财富和健康指标高度相关。最后，心血管、液体管理和透析充分性分组与教育、财富和医疗资源指标相关。
我们确定了与透析变量相关的社会经济指标。这项产生假设的研究可能有助于分析全球健康指标如何影响HD的可及性、治疗提供、透析治疗特征和结局。
