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一名心肺移植受者发生基于甲型H1N1流感肺炎的严重细菌重叠感染。

Severe bacterial superinfection based on influenza A (H1N1) pneumonia in a heart-lung transplant recipient.

作者信息

Yildirim Y, Pecha S, Sill B, Deuse T, Reichenspurner H

机构信息

Department of Cardiovascular Surgery, University Heart Center, Hamburg, Germany.

出版信息

Thorac Cardiovasc Surg. 2013 Apr;61(3):255-7. doi: 10.1055/s-0032-1331895. Epub 2013 Jan 23.

DOI:10.1055/s-0032-1331895
PMID:23344758
Abstract

A 47-year-old heart-lung transplant recipient presented to our outpatient transplant clinic with respiratory infection. Her nose and throat swabs for influenza A (H1N1) infection were negative. Broncheoalveolar lavage showed a positive result for H1N1 infection. Antiviral therapy was initiated. Because of superinfection with Pseudomonas aeruginosa and Aspergillus terreus, her clinical condition worsened. The clinical condition of the patient improved with antibiotic and antifungal treatment. Negative nose and throat swab results cannot rule out H1N1 infection safely. We therefore advocate to routinely perform broncheoalveolar lavage.

摘要

一名47岁的心肺移植受者因呼吸道感染前来我们的门诊移植诊所就诊。她的甲型H1N1流感感染鼻拭子和咽拭子检测结果均为阴性。支气管肺泡灌洗显示H1N1感染呈阳性结果。于是开始了抗病毒治疗。由于合并铜绿假单胞菌和土曲霉的二重感染,她的临床状况恶化。经过抗生素和抗真菌治疗,患者的临床状况有所改善。鼻拭子和咽拭子检测结果为阴性并不能安全地排除H1N1感染。因此,我们主张常规进行支气管肺泡灌洗。

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