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尸检酒精报告的有效性。

Validity of post-mortem alcohol reports.

作者信息

Karhunen P J, Penttilä A

机构信息

Department of Forensic Medicine, University of Helsinki, Finland.

出版信息

Alcohol Alcohol. 1990;25(1):25-32.

PMID:2334492
Abstract

The drinking behaviour of 95 consecutive men subjected to medicolegal autopsy in Helsinki was studied by interviewing a relative or friend of the deceased. Sufficient data for estimating the daily alcohol dose were obtained in 61 (64%) of the cases. Of these men, 21 (34%) were reported to drink at least an average of 80 g of alcohol daily. The validity of post-mortem alcohol reports was assessed by comparing the occurrence of alcohol-related diseases, toxicological data as well as the cause and manner of death with the reported alcohol consumption. Men whose reported daily alcohol consumption exceeded 80 g (mean 230 g) differed from men reported to drink less than 10 g (mean 3 g) in their more common incidence of positive post-mortem alcohol test (P less than 0.0005), fatty liver (P less than 0.001), enlarged liver (P less than 0.01), alcoholic hepatitis (P less than 0.05), chronic pancreatitis (P less than 0.01), and in their lower rate of death from cardiovascular diseases (P less than 0.05). The present results indicate that interviews with relatives or friends provide reliable data on the drinking behaviour of the deceased. At autopsy, the most sensitive tests coinciding with high consumption of alcohol in post-mortem alcohol reports but not with each other were positive post-mortem blood alcohol and the occurrence of fatty liver.

摘要

通过与死者的亲属或朋友进行访谈,对在赫尔辛基接受法医尸检的95名连续男性的饮酒行为进行了研究。在61例(64%)病例中获得了估计每日酒精摄入量的足够数据。在这些男性中,据报告有21例(34%)每天至少平均饮用80克酒精。通过将与酒精相关疾病的发生率、毒理学数据以及死亡原因和方式与报告的酒精消费量进行比较,评估了死后酒精报告的有效性。报告每日酒精消费量超过80克(平均230克)的男性与报告饮酒量少于10克(平均3克)的男性相比,死后酒精检测呈阳性(P<0.0005)、脂肪肝(P<0.001)、肝脏肿大(P<0.01)、酒精性肝炎(P<0.05)、慢性胰腺炎(P<0.01)的发生率更高,而死于心血管疾病的比率更低(P<0.05)。目前的结果表明,与亲属或朋友的访谈可为死者的饮酒行为提供可靠数据。在尸检时,与死后酒精报告中高酒精消费量相符但彼此不相符的最敏感检测是死后血液酒精阳性和脂肪肝的出现。

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Sudden unexpected death in alcohol misuse--an unrecognized public health issue?酒精滥用导致的突发性意外死亡——一个未被识别的公共卫生问题?
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