Linz Luke A, Burke Leandra H, Miller Lisa A
College of Osteopathic Medicine, Michigan State University, Lansing, Michigan, USA.
BMJ Case Rep. 2013 Jan 22;2013:bcr2012007562. doi: 10.1136/bcr-2012-007562.
A 50-year-old woman with a history of multiple recurrent incisional hernias and multiple comorbidities received two different porcine dermal implants during the same procedure due to the availability of products in stock. At 3.5 months following this procedure, the patient developed a secondary hernia inferior and lateral to the site of previous surgery. Both the implants were biopsied and sent for pathological evaluation. One implant was compliant and well integrated while the other was non-compliant and exhibited extensive foreign body reaction. In this case report, we examine the differences between the two porcine implants that may have caused them to react so differently in the same subject under the same conditions.
一名有多次复发性切口疝病史且合并多种疾病的50岁女性,由于有库存产品,在同一次手术中接受了两种不同的猪真皮植入物。该手术后3.5个月,患者在先前手术部位的下方和外侧出现了继发性疝。对两个植入物都进行了活检并送去做病理评估。一个植入物顺应性好且整合良好,而另一个则不符合要求并表现出广泛的异物反应。在本病例报告中,我们研究了这两种猪植入物之间的差异,这些差异可能导致它们在相同条件下的同一受试者体内产生如此不同的反应。