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艰难梭菌所致伪膜性结肠炎作为会阴坏死性筋膜炎的一个病因

Pseudomembranous colitis due to Clostridium difficile as a cause of perineal necrotising fasciitis.

作者信息

Duburcq Thibault, Parmentier-Decrucq Erika, Poissy Julien, Mathieu Daniel

机构信息

Service d'Urgence Respiratoire, Réanimation Médicale et Medecine Hyperbare, Université de Lille II et Centre Hospitalier et Universitaire de Lille, Lille, France.

出版信息

BMJ Case Rep. 2013 Jan 22;2013:bcr2012008153. doi: 10.1136/bcr-2012-008153.

DOI:10.1136/bcr-2012-008153
PMID:23345501
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3604471/
Abstract

Although rare, pseudomembranous colitis may be a cause of perineal necrotising fasciitis in a context of immunosuppression, as in the case we report. This origin must be quickly identified because the therapeutic management, especially surgery, is unlikely to be the same as usual. Similarly, antibiotic treatment is also a matter of discussion due to the potential deleterious role of antibiotics in pseudomembranous colitis.

摘要

尽管罕见,但在免疫抑制的情况下,伪膜性结肠炎可能是会阴部坏死性筋膜炎的一个病因,如我们报道的病例。必须迅速识别这种病因,因为治疗管理,尤其是手术,可能与通常情况不同。同样,由于抗生素在伪膜性结肠炎中可能具有有害作用,抗生素治疗也存在争议。

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本文引用的文献

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Best strategies in recurrent or persistent Clostridium difficile infection.复发性或持续性艰难梭菌感染的最佳策略。
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European evidence-based Consensus on the diagnosis and management of ulcerative colitis: Definitions and diagnosis.欧洲溃疡性结肠炎诊断与管理循证共识:定义与诊断
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Clostridium difficile--more difficult than ever.艰难梭菌——比以往任何时候都更难对付。
N Engl J Med. 2008 Oct 30;359(18):1932-40. doi: 10.1056/NEJMra0707500.
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