Leung A F, McCormick L M
Department of Physics and Astronomy, California State University, Long Beach, California.
J Biol Phys. 1997 Jun;23(2):67-72. doi: 10.1023/A:1004908708162.
The calcium wave subsequent to fertilization of the egg is analyzed interms of an electrical equivalent circuit. The circuit consists of aswitch, capacitor, an inductor, and a resistor. The switch symbolizes aseries of chemical reactions initiated by the sperm the lead to thedevelopment of the calcium wave. Its closure signifies the onset of thecalcium wave. The capacitor and inductor represent the endoplasmicreticulum. The capacitive component of the endoplasmic reticulum controlsthe release of calcium ions while the inductive component regulates thesequestration of clacium ions. The resistor represents the inductor andcytoplasm and has very low resistance. The analysis of the circuit showsthat the period of the calcium oscillations is proportional to the size ofthe egg. It agrees with the measurements on various types of eggs.
根据一个等效电路来分析卵子受精后的钙波。该电路由一个开关、一个电容器、一个电感器和一个电阻器组成。开关象征着由精子引发的一系列化学反应，这些反应导致了钙波的产生。开关闭合表示钙波开始。电容器和电感器代表内质网。内质网的电容成分控制钙离子的释放，而电感成分调节钙离子的隔离。电阻器代表线粒体和细胞质，电阻非常低。对该电路的分析表明，钙振荡的周期与卵子大小成正比。这与对各种类型卵子的测量结果相符。
