Kellokumpu-Lehtinen P, Huovinen R, Nikkanen V
Department of Radiotherapy, University Central Hospital, Turku, Finland.
Acta Oncol. 1990;29(2):175-8. doi: 10.3109/02841869009126541.
Survival and esophageal passage were studied retrospectively in 106 patients with inoperable esophageal carcinoma treated with radiotherapy during the years 1972 to 1983. The survival rates were 30%, 13% and 7% at one, two and three years respectively. The survival rate for the female patients was significantly better than for the males throughout these three years; 9% of the female patients lived for three years compared to only 3% of the male patients. Forty-two percent of the patients received 'radical' irradiation (greater than 50 Gy). The 3-year survival rate was 16% after a tumor dose of 50 Gy or more, and zero with a dose less than 50 Gy, but this difference might be explained by selection factors, such as patients in poor general condition not receiving 'radical' irradiation. Esophageal passage after radiotherapy could be evaluated in 62 patients, and 22 (35%) of them required feeding gastrostomy due to esophageal discontinuity, most often within one year after completion of radiotherapy. It is concluded that radiotherapy has only a slight effect on the prognosis of inoperable esophageal carcinoma.
对1972年至1983年间接受放疗的106例无法手术的食管癌患者的生存情况和食管通畅情况进行了回顾性研究。1年、2年和3年的生存率分别为30%、13%和7%。在这三年中，女性患者的生存率明显高于男性；9%的女性患者存活了三年，而男性患者仅为3%。42%的患者接受了“根治性”放疗（大于50 Gy）。肿瘤剂量达到50 Gy或更高时，3年生存率为16%，剂量低于50 Gy时为零，但这种差异可能是由选择因素造成的，比如一般状况较差的患者未接受“根治性”放疗。62例患者放疗后的食管通畅情况可进行评估，其中22例（35%）因食管连续性中断需要行胃造瘘术进食，多数发生在放疗结束后一年内。结论是，放疗对无法手术的食管癌预后影响甚微。
