葡萄糖和尿酸的太赫兹时域光谱学
Terahertz time-domain spectroscopy of glucose and uric Acid.
作者信息
Upadhya P C, Shen Y C, Davies A G, Linfield E H
机构信息
Cavendish Laboratory, University of Cambridge, Madingley Road, Cambridge, CB3 0HE UK.
出版信息
J Biol Phys. 2003 Jun;29(2-3):117-21. doi: 10.1023/A:1024476322147.
Abstract
We report the use ofterahertz time-domain spectroscopy for thestudy of two therapeutic bio-molecules:glucose and uric acid. Terahertztransmission spectra of crystalline samplesof both molecules were measured between 0.1-3.0 THz using an evacuated spectroscopysystem. We propose that the stereo-isomersof glucose show spectral featuresoriginating from intermolecular vibrationalmodes, as do uric acid and its derivativemolecule, allantoin. In addition, wepresent a full temperature dependence ofthe terahertz absorption of L-glucose.
摘要
我们报告了利用太赫兹时域光谱技术对两种治疗性生物分子
葡萄糖和尿酸进行研究的情况。使用真空光谱系统在0.1 - 3.0太赫兹之间测量了这两种分子晶体样品的太赫兹透射光谱。我们提出，葡萄糖的立体异构体呈现出源于分子间振动模式的光谱特征，尿酸及其衍生物尿囊素也是如此。此外，我们还给出了L - 葡萄糖太赫兹吸收的完整温度依赖性。
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