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使用太赫兹光谱成像技术测量动物器官组织中的含水量。

Measuring water contents in animal organ tissues using terahertz spectroscopic imaging.

作者信息

Lee Kyumin, Jeoung Kiyong, Kim Sang Hoon, Ji Young-Bin, Son Hyeyoung, Choi Yuna, Huh Young-Min, Suh Jin-Suck, Oh Seung Jae

机构信息

Graduate Program for Nanomedical Science, Yonsei University, Seoul 03722, South Korea.

YUHS-KRIBB Medical Convergence Research Institute, Yonsei University, Seoul 03722, South Korea.

出版信息

Biomed Opt Express. 2018 Mar 8;9(4):1582-1589. doi: 10.1364/BOE.9.001582. eCollection 2018 Apr 1.

DOI:10.1364/BOE.9.001582
PMID:29675303
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5905907/
Abstract

We investigated the water contents in several organ tissues such as the liver, spleen, kidney, and brain tissue of rats using the terahertz spectroscopic imaging technique. The water contents of the tissues were determined by using a simple equation containing the absorption coefficients of fresh and lyophilized tissues and water. We compared the measured water contents with the difference in mass of tissues before and after lyophilization. All results showed a good match except for the kidney, which has several Bowman's capsules.

摘要

我们使用太赫兹光谱成像技术研究了大鼠肝脏、脾脏、肾脏和脑组织等多种器官组织中的含水量。通过一个包含新鲜组织、冻干组织和水的吸收系数的简单公式来测定组织的含水量。我们将测量得到的含水量与冻干前后组织质量的差值进行了比较。除了具有多个肾小囊的肾脏外,所有结果都显示出良好的匹配度。

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本文引用的文献

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Sci Rep. 2016 Oct 26;6:36040. doi: 10.1038/srep36040.
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THz Medical Imaging: Hydration Sensing.太赫兹医学成像:水分感应
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Feasibility of terahertz reflectometry for discrimination of human early gastric cancers.太赫兹反射测量法鉴别人类早期胃癌的可行性
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4
Terahertz spectroscopic imaging and properties of gastrointestinal tract in a rat model.大鼠模型中胃肠道的太赫兹光谱成像及特性
Biomed Opt Express. 2014 Nov 5;5(12):4162-70. doi: 10.1364/BOE.5.004162. eCollection 2014 Dec 1.
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Terahertz time-domain spectroscopy of glucose and uric Acid.葡萄糖和尿酸的太赫兹时域光谱学
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Terahertz-wave water concentration and distribution measurement in thin biotissue based on a novel sample preparation.基于新型样品制备的太赫兹波薄生物组织水浓度和分布测量。
Phys Med Biol. 2011 Jul 21;56(14):4517-27. doi: 10.1088/0031-9155/56/14/018. Epub 2011 Jun 30.
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Phys Med Biol. 2010 Dec 21;55(24):7587-96. doi: 10.1088/0031-9155/55/24/013. Epub 2010 Nov 19.
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Tissue characterization using terahertz pulsed imaging in reflection geometry.在反射几何结构中使用太赫兹脉冲成像进行组织表征。
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The impact of hydration changes in fresh bio-tissue on THz spectroscopic measurements.新鲜生物组织中水分变化对太赫兹光谱测量的影响。
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