Department of Internal Medicine, Elsinore Hospital, Elsinore, Denmark ; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Int J Gen Med. 2013;6:9-12. doi: 10.2147/IJGM.S38158. Epub 2013 Jan 9.
Patients with univentricular heart malformations are at increased risk of suffering from thromboembolic events. We present a case of a 19-year-old woman born with a univentricular heart who suffered a major stroke while being treated with only salicylic acid. At least 20% of patients with univentricular hearts have been reported to experience thromboembolic events, of which 25% are fatal. Despite the high incidence of thromboembolic events, no consensus has been reached regarding the role of long-term anti-thrombotic treatment in this group of patients. This lack of consensus warrants future studies that compare the different therapeutic strategies.
患有单心室心脏畸形的患者发生血栓栓塞事件的风险增加。我们报告了一例 19 岁的女性，出生时患有单心室心脏畸形，在仅接受水杨酸治疗时发生了严重中风。据报道，至少 20%的单心室心脏畸形患者经历过血栓栓塞事件，其中 25%是致命的。尽管血栓栓塞事件的发生率很高，但对于这组患者长期抗血栓治疗的作用尚未达成共识。这种缺乏共识需要未来的研究来比较不同的治疗策略。
