Lin E S, Jones M J, Mottram S D, Smith B E, Smith G
University Department of Anaesthesia, Leicester Royal Infirmary.
Br J Anaesth. 1990 Apr;64(4):453-9. doi: 10.1093/bja/64.4.453.
We have studied the relationship between gas exchange and mechanical frequency response during high frequency jet ventilation (HFJV) at 0.5-5.0 Hz in anaesthetized pigs. The mechanical gain curve showed a minimal "anti-resonant" response at 0.8 Hz (f1) and a maximal "resonant" response at 5.0 Hz (f2). This finding may be explained by modelling the thorax and abdomen as a system of coupled masses and compliances which undergo two different modes of forced oscillation in the frequency range studied. Gas exchange was optimal in the frequency range between the minimal and maximal responses. The tidal volumes produced were greater than anatomical deadspace, suggesting that gas transport was mainly convective in this range.
我们研究了麻醉猪在0.5 - 5.0赫兹高频喷射通气（HFJV）过程中气体交换与机械频率响应之间的关系。机械增益曲线显示在0.8赫兹（f1）处有最小的“反共振”响应，在5.0赫兹（f2）处有最大的“共振”响应。这一发现可以通过将胸腔和腹部建模为一个耦合质量和顺应性系统来解释，该系统在研究的频率范围内经历两种不同的强迫振荡模式。气体交换在最小和最大响应之间的频率范围内最佳。产生的潮气量大于解剖无效腔，这表明该范围内的气体传输主要是对流性的。
