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胃尤文肉瘤;尤文肉瘤罕见病例及新治疗策略建议。

Ewing's Sarcoma of the Stomach; Rare Case of Ewing's Sarcoma and Suggestion of New Treatment Strategy.

机构信息

Department of Surgery, Chosun University Hospital, School of Medicine, Chosun University, Gwangju, Korea.

出版信息

J Gastric Cancer. 2012 Dec;12(4):258-61. doi: 10.5230/jgc.2012.12.4.258. Epub 2012 Dec 31.

Abstract

Ewing's sarcoma is a neoplasm of the undifferenciated small round cells, which generally affects the bone and deep soft tissues of children and adolescents. We present a case of gastric Ewing's sarcoma; a 35-year-old female who had no symptoms. While she was at a routine medical checkup, a protruding mass in her gastric antrum was incidentally found on esophagogastroduodenoscopy. Endoscopic ultrasonogram showed a submucosal mass on the same lesion and a laparosopic wedge resection was done. Pathologic gross findings showed a granular grape appearance tissue and histoloigc examination revealed a small round cell tumor with CD 99 immunoexpression positive. In general, a combined modality therapy for Ewing's sarcoma such as surgical resection with chemotherapy, is accepted as an effective method. However, this patient had no adjuvant chemotherapy after surgery and she has no recurrence for eleven months.

摘要

尤因氏肉瘤是一种未分化的小圆细胞肿瘤,通常影响儿童和青少年的骨骼和深部软组织。我们报告一例胃尤因氏肉瘤;一名 35 岁女性,无任何症状。在例行体检时,上消化道内镜检查偶然发现胃窦部有一隆起性肿块。内镜超声显示同一病变的黏膜下肿块,并进行腹腔镜楔形切除术。病理大体观察显示颗粒状葡萄状组织,组织学检查显示小圆细胞肿瘤,CD99 免疫表达阳性。一般来说,尤因氏肉瘤的综合治疗方法,如手术切除联合化疗,被认为是一种有效的方法。然而,该患者术后未行辅助化疗,至今已无复发 11 个月。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ff1/3543978/8d49b95073f2/jgc-12-258-g001.jpg

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