Zare Farzaneh, Shahbazi Niloofar, Faraji Navid, Goli Rasoul, Mostafaei Behnam, Anari Sina
Department of Nursing, School of Nursing and Midwifery, Urmia University of Medical Sciences, Urmia, Iran.
Department of Nursing, School of Nursing and Midwifery, Islamic Azad University Zarand, Kerman, Iran.
Int J Surg Case Rep. 2023 Jul;108:108380. doi: 10.1016/j.ijscr.2023.108380. Epub 2023 Jun 6.
Ewing's sarcoma, a highly malignant bone tumor, typically affects the pelvis and long bones of the lower extremities in children and young adults; primary involvement of the skull is rare. Primary Ewing's sarcoma arising from the skull is very rare. In most cases, this disease is fatal, although the prognosis of Ewing sarcoma improves with radiation and chemotherapy after surgery.
This case is about 25-year-old woman who was referred to Omid Hospital in Urmia because of frequent headaches, where a tumor mass was found according to the results of CT scan. Biopsy confirmed small round cell sarcoma as the diagnosis. Chemotherapy was ineffective and tumor growth was unstoppable, causing the patient to die after 3 months.
Ewing's sarcoma can affect various parts of the human body, including bone and soft tissue, but rarely the skull. Ewing's sarcoma typically grows extradural and often reaches a very large size before invading the skull or being detected clinically.
In most cases, Ewing's sarcoma is fatal, although the prognosis of this disease improves with radiation and chemotherapy after surgery.
尤因肉瘤是一种高度恶性的骨肿瘤，通常影响儿童和年轻成人的骨盆及下肢长骨；颅骨原发性受累罕见。起源于颅骨的原发性尤因肉瘤极为罕见。在大多数情况下，这种疾病是致命的，尽管尤因肉瘤在手术后通过放疗和化疗，其预后有所改善。
本病例为一名25岁女性，因频繁头痛被转诊至乌尔米耶的奥米德医院，根据CT扫描结果发现了一个肿瘤块。活检确诊为小圆细胞肉瘤。化疗无效，肿瘤持续生长，导致患者在3个月后死亡。
尤因肉瘤可累及人体各个部位，包括骨骼和软组织，但很少累及颅骨。尤因肉瘤通常在硬膜外生长，在侵入颅骨或临床检测到之前，往往会长得非常大。
在大多数情况下，尤因肉瘤是致命的，尽管这种疾病在手术后通过放疗和化疗，其预后有所改善。
