Department of Health Policy and Management, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7411, USA.
Health Serv Res. 2013 Apr;48(2 Pt 2):753-72. doi: 10.1111/1475-6773.12028. Epub 2013 Jan 24.
To use coronary revascularization choice to illustrate the application of a method simulating a treatment's effect on subsequent resource use.
Medicare inpatient and outpatient claims from 2002 to 2008 for patients receiving multivessel revascularization for symptomatic coronary disease in 2003-2004.
This retrospective cohort study of 102,877 beneficiaries assessed survival, days in institutional settings, and Medicare payments for up to 6 years following receipt of percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG).
A three-part estimator designed to provide robust estimates of a treatment's effect in the setting of mortality and censored follow-up was used. The estimator decomposes the treatment effect into effects attributable to survival differences versus treatment-related intensity of resource use.
After adjustment, on average CABG recipients survived 23 days longer, spent an 11 additional days in institutional settings, and had cumulative Medicare payments that were $12,834 higher than PCI recipients. The majority of the differences in institutional days and payments were due to intensity rather than survival effects.
In this example, the survival benefit from CABG was modest and the resource implications were substantial, although further adjustments for treatment selection are needed.
以冠状动脉血运重建术的选择为例,说明一种模拟治疗对后续资源利用影响的方法的应用。
2002 年至 2008 年接受多支血管血运重建术治疗症状性冠状动脉疾病的患者的医疗保险住院和门诊索赔数据,这些患者于 2003-2004 年接受治疗。
本回顾性队列研究共纳入了 102877 名受益人的数据,评估了接受经皮冠状动脉介入治疗(PCI)或冠状动脉旁路移植术(CABG)后长达 6 年的生存情况、住院天数和医疗保险支付情况。
使用了一种三部分估计器,旨在为死亡率和删失随访背景下的治疗效果提供稳健的估计。该估计器将治疗效果分解为生存差异和与治疗相关的资源利用强度的影响。
经过调整,CABG 组的平均生存时间延长了 23 天,住院天数增加了 11 天,医疗保险支付金额比 PCI 组高 12834 美元。住院天数和支付金额的大部分差异归因于资源利用强度,而非生存效果。
在这个例子中,CABG 的生存获益适中,但资源利用的影响较大,尽管需要进一步调整治疗选择。