Regional Dermatology Training Center, Moshi, Tanzania.
Int J Dermatol. 2013 Feb;52(2):191-4. doi: 10.1111/j.1365-4632.2012.05600.x.
Vitiligo is an acquired, predominantly asymptomatic, depigmenting disorder with profound psychological effects.
This was a cross-sectional study conducted at the Regional Dermatology Training Center in Moshi, Tanzania. All 88 patients with vitiligo older than 15 years of age who attended the skin clinic from October 2009 to April 2010 were recruited. Data were collected using a structured questionnaire, Dermatology Life Quality Index questionnaire (DLQI), and Vitiligo European Task Force form.
Vitiligo moderately affects patient's quality of life, as indicated by a DLQI mean score of 7.2 ± 4.8. The mean age was 41 years with a male/female ratio of 1:1.7. The mean age of disease onset was 33.5 years (range 16-83 years); vitiligo vulgaris was the most common disease form seen (n = 49). None of the factors considered were found to be significantly associated with impaired quality of life on multivariate analysis. The majority of patients (73.8%) perceived that their disease was moderate to severe in contrast to the clinical grading in which only 49.2% patients were classified as having mild disease. This difference in classification of disease severity was statistically significant (Fishers exact test = 0.001).
Patients with vitiligo of African descent have a moderate impairment of quality of life.
白癜风是一种获得性、主要无症状的色素减退性疾病，对患者心理影响深远。
这是一项在坦桑尼亚莫希地区皮肤病培训中心进行的横断面研究。2009 年 10 月至 2010 年 4 月期间，所有在皮肤科诊所就诊的年龄大于 15 岁的 88 例白癜风患者均纳入研究。使用结构化问卷、皮肤病生活质量指数问卷（DLQI）和白癜风欧洲工作组表单收集数据。
白癜风对患者的生活质量有一定影响，DLQI 平均得分为 7.2 ± 4.8。患者平均年龄为 41 岁，男女比例为 1:1.7。发病年龄平均为 33.5 岁（16-83 岁）；寻常型白癜风最为常见（n = 49）。多因素分析未发现任何因素与生活质量受损显著相关。大多数患者（73.8%）认为他们的疾病为中重度，而临床分级中仅有 49.2%的患者被归类为轻度疾病。这种疾病严重程度分类的差异具有统计学意义（Fisher 确切检验=0.001）。
非洲裔白癜风患者的生活质量有中度受损。
