唾液可替宁浓度与日本年轻女性牙周病的相关性：九州冲绳母婴健康研究。
Salivary cotinine concentrations and prevalence of periodontal disease in young Japanese women: the Kyushu Okinawa maternal and child health study.
机构信息
Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
出版信息
J Periodontol. 2013 Dec;84(12):1724-9. doi: 10.1902/jop.2013.120670. Epub 2013 Jan 24.
BACKGROUND
The authors investigated the relationship between objectively assessed tobacco smoke exposure and periodontal disease.
METHODS
This cross-sectional study included 1,103 women with a mean age of 31.5 years. Information on potential confounding factors was obtained through a self-administered questionnaire. Periodontal disease was defined as positive if a woman had at least one tooth with a probing depth of ≥ 3.5 mm. Exposure to tobacco smoke was determined based on salivary cotinine concentration. Adjustment was made for age, region of residence, household income, education, toothbrushing frequency, and use of an interdental brush.
RESULTS
The prevalence of periodontal disease was 11.3%. Salivary cotinine concentration was independently positively associated with the prevalence of periodontal disease: the adjusted odds ratio for every 1-unit (ng/mL) increase in salivary cotinine was 1.004 (95% confidence interval: 1.000 to 1.007).
CONCLUSION
Salivary cotinine concentrations were positively associated with the prevalence of periodontal disease among young women.
背景
本研究旨在调查客观评估的烟草烟雾暴露与牙周病之间的关系。
方法
本横断面研究纳入了 1103 名年龄平均为 31.5 岁的女性。通过问卷调查获取了可能的混杂因素信息。如果女性至少有一颗牙齿的探诊深度≥3.5mm，则定义为患有牙周病。根据唾液可替宁浓度来确定吸烟暴露情况。在调整年龄、居住地区、家庭收入、教育程度、刷牙频率和使用牙间刷等因素后进行分析。
结果
牙周病的患病率为 11.3%。唾液可替宁浓度与牙周病的患病率呈独立正相关：每增加 1 个单位（ng/ml）的唾液可替宁，牙周病的调整优势比为 1.004（95%置信区间：1.000 至 1.007）。
结论
唾液可替宁浓度与年轻女性牙周病的患病率呈正相关。
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