Long sleep duration and frequent day-time naps of the infants can be protective for vigabatrin-induced visual field defects.
作者信息
Ekici Barış, Yıldırım Yeliz, Uçar Didar, Tatlı Burak
机构信息
Department of Pediatric Neurology, Istanbul Medical Faculty, Fatih/Istanbul, Turkey.
出版信息
Ann Indian Acad Neurol. 2012 Oct;15(4):350-1. doi: 10.4103/0972-2327.104359.
Abstract
摘要
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Long sleep duration and frequent day-time naps of the infants can be protective for vigabatrin-induced visual field defects.婴儿睡眠时间长且白天频繁小睡可能对vigabatrin诱导的视野缺损具有保护作用。
Ann Indian Acad Neurol. 2012 Oct;15(4):350-1. doi: 10.4103/0972-2327.104359.
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本文引用的文献
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Visual fields at school-age in children treated with vigabatrin in infancy.婴儿期接受vigabatrin治疗的儿童在学龄期的视野情况。
Epilepsia. 2009 Feb;50(2):206-16. doi: 10.1111/j.1528-1167.2008.01961.x.
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Influence of dietary melatonin on photoreceptor survival in the rat retina: an ocular toxicity study.膳食褪黑素对大鼠视网膜光感受器存活的影响：一项眼毒性研究。
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Vigabatrin and visual field defects in pediatric epilepsy patients.儿童癫痫患者中的vigabatrin与视野缺损
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Acute vigabatrin retinotoxicity in albino rats depends on light but not GABA.白化大鼠急性氨己烯酸视网膜毒性取决于光照而非γ-氨基丁酸。
Epilepsia. 2004 Sep;45(9):1043-8. doi: 10.1111/j.0013-9580.2004.01004.x.
5
Vigabatrin, the GABA-transaminase inhibitor, damages cone photoreceptors in rats.γ-乙烯基γ-氨基丁酸（Vigabatrin），一种γ-氨基丁酸转氨酶抑制剂，会损害大鼠的视锥光感受器。
Ann Neurol. 2004 May;55(5):695-705. doi: 10.1002/ana.20081.
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Visual field constriction: accumulation of vigabatrin but not tiagabine in the retina.视野缩窄：维加巴胺而非噻加宾在视网膜中的蓄积。
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Exp Gerontol. 2001 Jul;36(7):1083-100. doi: 10.1016/s0531-5565(01)00120-6.
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Human brain GABA levels rise rapidly after initiation of vigabatrin therapy.
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