Zborek A, Krzyzowska-Gruca S, Gruca S
Department of Tumor Biology, Institute of Oncology, Gliwice, Poland.
Cell Biol Int Rep. 1990 Jan;14(1):79-88. doi: 10.1016/0309-1651(90)90073-8.
A fraction enriched in interchromatin granules (IG) has been obtained from isolated liver nuclei by digestion with DNase I and extraction with salt solutions. The fraction contains interchromatin granules in the form of conglomerations and some contaminating material of nucleolar and nuclear matrix origin. The ultrastructure of the fraction enriched in IG and electrophoretic patterns of proteins are described.
通过用DNA酶I消化并盐溶液提取,从分离的肝细胞核中获得了富含染色质间颗粒(IG)的部分。该部分包含呈团聚体形式的染色质间颗粒以及一些源自核仁与核基质的污染物质。描述了富含IG部分的超微结构和蛋白质的电泳图谱。