原发性系统性淀粉样变性的皮肤表现。
Skin involvement in primary systemic amyloidosis.
机构信息
Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
出版信息
Mediterr J Hematol Infect Dis. 2013;5(1):e2013005. doi: 10.4084/MJHID.2013.005. Epub 2013 Jan 2.
Abstract
Primary systemic amyloidosis is a rare disease. It primarily involves kidney, heart, peripheral nerves and liver. Intracutaneous hemorrhage manifesting in the form of petechiae, purpura and ecchymoses due to infiltration of blood vessel walls by amyloid deposits are the most common skin lesions. We report a case of primary systemic amyloidosis with multiple, non-itchy, papular lesions in lower eyelids and lower chest wall bilaterally. Diagnosis was confirmed in this case by biopsy of skin lesions using congo red staining. Papular eruptions as seen in index patient are relatively uncommon form of skin manifestations.
摘要
原发性系统性淀粉样变是一种罕见的疾病。它主要累及肾脏、心脏、周围神经和肝脏。由于血管壁被淀粉样沉积物浸润，导致皮肤出现瘀点、瘀斑和血肿，这是最常见的皮肤病变。我们报告了一例原发性系统性淀粉样变患者，其双侧下眼睑和下胸部壁有多个、非瘙痒性、丘疹样病变。通过刚果红染色对皮肤病变进行活检，在本例中确诊了诊断。丘疹性发疹在该患者中所见的形式相对较为罕见的皮肤表现形式。
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