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心脏手术后的肺损伤和急性呼吸窘迫综合征。

Lung injury and acute respiratory distress syndrome after cardiac surgery.

机构信息

Division of Pulmonary and Critical Care Medicine, Department of Medicine, The Johns Hopkins University, Baltimore, MD 21224, USA.

出版信息

Ann Thorac Surg. 2013 Mar;95(3):1122-9. doi: 10.1016/j.athoracsur.2012.10.024. Epub 2013 Jan 23.

Abstract

As many as 20% of patients undergoing cardiac surgery will have acute respiratory distress syndrome during the perioperative period, with a mortality as high as 80%. If patients at risk can be identified, preventative measures can be taken and may improve outcomes. Care for patients with acute respiratory distress syndrome is supportive, with low tidal volume ventilation being the mainstay of therapy. Careful fluid management, minimization of blood product transfusion, appropriate nutrition, and early physical rehabilitation may improve outcomes. In cases of refractory hypoxemia, rescue therapies such as recruitment maneuvers, high-frequency oscillatory ventilation, and extracorporeal membrane oxygenation may preserve life.

摘要

多达 20%的心脏手术患者在围手术期会出现急性呼吸窘迫综合征,死亡率高达 80%。如果能识别出高危患者,可以采取预防措施,可能会改善预后。急性呼吸窘迫综合征患者的治疗以支持性治疗为主,小潮气量通气是治疗的主要方法。仔细的液体管理、减少血制品输注、适当的营养和早期的身体康复可能会改善预后。对于顽固性低氧血症的患者,可采用肺复张手法、高频振荡通气和体外膜氧合等抢救治疗来维持生命。

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