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In DOCK8 deficiency donor cell engraftment post-genoidentical hematopoietic stem cell transplantation is possible without conditioning.

作者信息

Al-Mousa Hamoud, Hawwari Abbas, Alsum Zobaida

出版信息

J Allergy Clin Immunol. 2013 Apr;131(4):1244-5. doi: 10.1016/j.jaci.2012.12.663. Epub 2013 Jan 23.

DOI:10.1016/j.jaci.2012.12.663
PMID:23352633
Abstract
摘要

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1
In DOCK8 deficiency donor cell engraftment post-genoidentical hematopoietic stem cell transplantation is possible without conditioning.在DOCK8缺陷型同基因造血干细胞移植后，无需预处理即可实现供体细胞植入。
J Allergy Clin Immunol. 2013 Apr;131(4):1244-5. doi: 10.1016/j.jaci.2012.12.663. Epub 2013 Jan 23.
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Multilineage hematopoietic engraftment after allogeneic peripheral blood stem cell transplantation without conditioning in SCID patients.重症联合免疫缺陷（SCID）患者在未进行预处理的情况下接受异基因外周血干细胞移植后的多谱系造血植入
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HLA-haploidentical donor transplantation in severe combined immunodeficiency.HLA 单倍体相合供者移植治疗严重联合免疫缺陷病。
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Food allergies can persist after myeloablative hematopoietic stem cell transplantation in dedicator of cytokinesis 8-deficient patients.在细胞分裂素8缺陷患者中，清髓性造血干细胞移植后食物过敏可能持续存在。
J Allergy Clin Immunol. 2016 Jun;137(6):1895-1898.e5. doi: 10.1016/j.jaci.2015.11.017. Epub 2016 Jan 28.
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Allogeneic stem cell transplantation using myeloablative and reduced-intensity conditioning in patients with major histocompatibility complex class II deficiency.同种异体干细胞移植使用清髓性和强度降低的预处理方案治疗主要组织相容性复合体 II 类缺陷患者。
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Hematopoietic stem cell transplantation for profound T-cell deficiency (combined immunodeficiency).造血干细胞移植治疗严重 T 细胞缺陷（联合免疫缺陷）。
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Clinical and immunological correction of DOCK8 deficiency by allogeneic hematopoietic stem cell transplantation following a reduced toxicity conditioning regimen.采用低毒性预处理方案后通过异基因造血干细胞移植对DOCK8缺陷进行临床和免疫纠正。
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[Hematopoietic stem cell transplantation in children with primary immunodeficiencies].[原发性免疫缺陷患儿的造血干细胞移植]
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Case report: Advanced age at transplantation and pre-emptive treatment with dupilumab in DOCK8 deficiency.病例报告：DOCK8缺陷患者移植时高龄及使用度普利尤单抗的抢先治疗
Front Immunol. 2025 Jan 28;15:1507494. doi: 10.3389/fimmu.2024.1507494. eCollection 2024.
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Successful treatment of DOCK8 deficiency by allogeneic hematopoietic cell transplantation from alternative donors.异基因造血细胞移植治疗 DOCK8 缺陷症。
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Clinical, immunological features and follow up of 20 patients with dedicator of cytokinesis 8 (DOCK8) deficiency.
20 例细胞分裂素 8 (DOCK8) 缺陷患者的临床、免疫学特征及随访。
Pediatr Allergy Immunol. 2020 Jul;31(5):515-527. doi: 10.1111/pai.13236. Epub 2020 Mar 11.
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Hematopoietic Stem Cell Transplantation as Treatment for Patients with DOCK8 Deficiency.造血干细胞移植治疗 DOCK8 缺陷患者。
J Allergy Clin Immunol Pract. 2019 Mar;7(3):848-855. doi: 10.1016/j.jaip.2018.10.035. Epub 2018 Nov 2.
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Recent Advances in DOCK8 Immunodeficiency Syndrome.DOCK8免疫缺陷综合征的最新进展
J Clin Immunol. 2016 Jul;36(5):441-9. doi: 10.1007/s10875-016-0296-z. Epub 2016 May 20.
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Hematopoietic stem cell transplantation outcomes for 11 patients with dedicator of cytokinesis 8 deficiency.11例细胞分裂8专一性蛋白缺乏患者的造血干细胞移植结果
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Eosinophilia Associated with Disorders of Immune Deficiency or Immune Dysregulation.与免疫缺陷或免疫失调疾病相关的嗜酸性粒细胞增多症。
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Matched related and unrelated donor hematopoietic stem cell transplantation for DOCK8 deficiency.DOCK8缺陷的匹配相关和无关供者造血干细胞移植
Biol Blood Marrow Transplant. 2015 Jun;21(6):1037-45. doi: 10.1016/j.bbmt.2015.01.022. Epub 2015 Jan 27.
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Hematopoietic stem cell transplantation for primary immunodeficiencies.原发性免疫缺陷的造血干细胞移植
Hematol Oncol Clin North Am. 2014 Dec;28(6):1157-70. doi: 10.1016/j.hoc.2014.08.006. Epub 2014 Sep 16.
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Flow cytometry diagnosis of dedicator of cytokinesis 8 (DOCK8) deficiency.细胞分裂素8（DOCK8）缺乏症的流式细胞术诊断
J Allergy Clin Immunol. 2014 Jul;134(1):221-3. doi: 10.1016/j.jaci.2014.02.023. Epub 2014 Apr 1.