Department of Clinical Radiology, University Hospitals of Munich Grosshadern, Munich, Germany.
Eur J Radiol. 2013 May;82(5):e219-24. doi: 10.1016/j.ejrad.2012.12.019. Epub 2013 Jan 24.
To implement and evaluate the accuracy of multislice dual-breath hold cine MR for analysis of global systolic and diastolic left ventricular function at 3T.
25 patients referred to cardiac MR underwent cine imaging at 3T (MAGNETOM Verio) using prospective triggered SSFP (TR 3.1 ms; TE 1.4 ms; FA 60°). Analysis of LV function was performed using a standard non-accelerated single-slice approach (STD) with multiple breath-holds and an accelerated multi-slice technique (TGRAPPA; R=4) encompassing the ventricles with 5 slices/breath-hold. Parameters of spatial and temporal resolution were kept identical (pixel: 1.9 × 2.5 mm(2); temporal resolution: 47 ms). Data of both acquisition techniques were analyzed by two readers using semiautomatic algorithms (syngoARGUS) with respect to EDV, ESV, EF, myocardial mass (MM), peak filling rate (PFR) and peak ejection rate (PER) including assessment of interobserver agreement.
Volumetric results of the TGRAPPA approach did not show significant differences to the STD approach for left ventricular ejection fraction (62.3 ± 10.6 vs. 61.0 ± 8.4, P=0.2), end-diastolic volume (135.8 ± 47.5 vs. 130.8 ± 46.4, P=0.07), endsystolic volume (53.0 ± 29.7 vs. 53.1 ± 32.7, P=0.99) and myocardial mass (114.2 ± 32.5 vs. 114.6±30.6, P=0.9). Moreover, a comparison of peak ejection rate (601.3 ± 190.2 vs. 590.8 ± 218.2, P=0.8) and peak filling rate (535.1±191.2 vs. 535.4 ± 210.7, P=0.99) did not reveal significant differences between the two groups. Limits in interobserver agreement were low for all systolic and diastolic parameters in both groups (P ≥ 0.05). Total acquisition time for STD was 273 ± 124 s and 34 ± 5 s for TGRAPPA (P ≤ 0.001). Evaluation time for standard and multislice approach was equal (10.8 ± 1.4 vs. 9.8 ± 2.1 min; P=0.08).
在 3T 上实施和评估多层双屏气电影磁共振成像（MR）分析整体收缩和舒张左心室功能的准确性。
25 名患者转至心脏磁共振检查，使用前瞻性触发的单次激发稳态进动（TR 3.1ms；TE 1.4ms；FA 60°）在 3T（MAGNETOM Verio）上进行电影成像。使用标准的无加速单切片方法（STD）和多切片技术（TGRAPPA；R=4）对 LV 功能进行分析，多切片技术用 5 个屏气的切片包绕心室。空间和时间分辨率的参数保持一致（像素：1.9×2.5mm²；时间分辨率：47ms）。两种采集技术的数据均由两名读者使用半自动算法（syngoARGUS）进行分析，参数包括 EDV、ESV、EF、心肌质量（MM）、峰值充盈率（PFR）和峰值射血率（PER），并评估观察者间的一致性。
TGRAPPA 方法的容积结果与 STD 方法相比，左心室射血分数（62.3±10.6 vs.61.0±8.4，P=0.2）、舒张末期容积（135.8±47.5 vs.130.8±46.4，P=0.07）、收缩末期容积（53.0±29.7 vs.53.1±32.7，P=0.99）和心肌质量（114.2±32.5 vs.114.6±30.6，P=0.9）无显著差异。此外，两组间的峰值射血率（601.3±190.2 vs.590.8±218.2，P=0.8）和峰值充盈率（535.1±191.2 vs.535.4±210.7，P=0.99）比较也无显著差异。两组所有收缩和舒张参数的观察者间一致性限制均较低（P≥0.05）。STD 的总采集时间为 273±124s，TGRAPPA 为 34±5s（P≤0.001）。标准和多切片方法的评估时间相同（10.8±1.4 vs.9.8±2.1min；P=0.08）。
